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Medical genetics

Breast Cancer Metastasis by Cell Behavior Instead of Genetics

The study find that the physicians could predict the likelihood that primary tumors will metastasize; therefore they would be able to choose the best treatment options for patients. Because However, current testing only reviews tumor genetics; which can mutate and change clinicians don’t fully understand why some cancers spread and others do not. What they do…

Medical genetics

Gene linked to rare progressive brain disease

The study find  that a group of mutations in a gene previously linked only to a rare progressive brain disease has been discovered by an international team co-led by Saudi investigators. Because The disorder congenital hypotonia, epilepsy, developmental delay, digit abnormalities; or CHEDDA is characterized by intellectual disability; reduced muscle tone and facial abnormalities. Progressive…

Medical genetics

Gene Fusions to Cancer Cell Fitness By Pharmacological

A gene is the basic unit of heredity in a living organism. All living things depend on genes. Genes hold the information to build and maintain their cells and pass genetic traits to offspring. Therefore A modern working definition of a gene is “a locatable region of genomic sequence; corresponding to a unit of inheritance, which is…

Medical genetics

Cancer Drug Inhibits DNA Repair in Cancer Cells

The researches find that interest in the cancer field in developing DNA repair inhibitors because they  greatly help treatments, therefore like radiotherapy and chemotherapy; Because that aim to destroy DNA in cancer cells;” said the senior author of the study at Yale Cancer Center, Peter M. Glazer, M.D., chair of the Department of Therapeutic Radiology;…

Medical genetics

Homology Domain Blocks the Growth of Mutation

mutated form earning its reputation as “undruggable.” Yet; the hunt for an Achilles’ heel continues, as cancers driven by KRAS mutations are both common and deadly. Because Scientists from Sanford Burnham Prebys and PHusis Therapeutics have shown that a compound called PHT-7.3 shrinks KRAS-driven tumors in mice. Therefore In contrast to directly targeting mutant KRAS;…

Medical genetics

Gene Mutation May Prevent Heart Disease

Gene mutation may prevent heart disease, according to researches co-led by a Boston University School of Public Health (BUSPH) researcher. Publish in the journal Circulation: Genomic and Precision Medicine; the study finds that protein-truncating variants in the apolipo protein B (APOB); gene are link to lower triglyceride and LDL cholesterol levels; and lower the risk…

Medical genetics

Pioneered the Use of DNA Websites to Unlock Cold Cases

Using an unconventional technique that relies on DNA submitted to online genealogy sites; therefore investigators have solved dozens of violent crimes; in many cases decades after they hit dead ends. Because Experts believe the technique is use to revive investigations into a vast number of cold cases across the US; including at least 100,000 unsolved major…

Medical genetics

Genetic Mutation May Not Be as Bad as You Think

Most people think carrying a gene variant associated with a disease means automatically getting that disease, according to Sekar Kathiresan; director of the Center of Genomic Medicine at Massachusetts General Hospital. That, he says, is not necessarily the case. In the early days of testing human genes; researchers began to ask a key question: How…

Medical genetics

Genome Editing Helps Decipher a Congenital Liver Disease

Congenital hepatic fibrosis (CHF) is a rare genetic disease that causes malformation and fibrosis (scarring) of the liver. Occurring in roughly one out of every 20,000 births, CHF can lead to an enlarged liver; impaired blood flow to the intestines (portal hypertension); infection of the bile ducts and liver failure. In severe cases, a liver…

Medical genetics

Scientists Discover New Antibiotic Resistance Gene

While sifting through the bacterial genome of salmonella, Cornell food scientists discovered mcr-9, a new, stealthy jumping gene so diabolical and robust that it resists one of the world’s few last-resort antibiotics. Doctors deploy the antibiotic colistin when all other infection-fighting options are exhausted. But resistance to colistin has emerged around the globe, threatening its efficacy.…

Medical genetics

A Genetic will He-alp to Test For Obesity Risk

Scientists who recently announced an experimental genetic test that can help predict obesity got immediate pushback from other researchers, who wonder whether it is really useful. The story behind this back-and-forth is, at its core, a question of when it’s worth diving deep into DNA data banks when there’s no obvious way to put that…

Medical genetics

Genetic Conditions Lead to Range of Overlapping Needs in Children

Deletions and duplications of DNA are responsible for wide-ranging developmental difficulties in children, finds a new study by Cardiff University. Lead author Professor Marianne van den Bree; from Cardiff University’s MRC Centre for Neuropsychiatric Genetics and Genomics, said: “We found that psychiatric health as well as development, learning and thinking, motor coordination and sleep quality were affected…