In genetics, an enhancer is a short region of DNA that can be bound by proteins to increase the likelihood that transcription of a particular gene will occur. These proteins are usually referred to as transcription factors.
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Researchers at the University of Helsinki and Folkhälsan Research Center have, together with their collaborators, for the first time demonstrated in a mouse model that partial restoration of respiratory chain function in mitochondria, which serve as cellular power plants, may be sufficient to prevent symptoms of a severe mitochondrial disorder entirely.
The World Health Organization (WHO) is creating a global panel to study human gene editing and the scientific, legal, social, and ethical challenges that surround it so the organization may move toward standards for oversight and governance.
In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility yield, and other traits of interest. Mostly, they're looking for needles in the enormous haystack that is the genome of an organism.
Medical researchers at Melbourne's Murdoch Children's Research Institute have discovered how a baby's sex is determined and it's not just about the XY chromosomes , but involves a 'regulator' that increases or decreases the gene activity which decides if we are male or female.
Why do we age? Despite more than a century of research (and a vast industry of youth-promising products), what causes our cells and organs to deteriorate with age is still unknown.
The largest-ever genetic study of people with moderate-to-severe asthma has revealed new insights into the underlying causes of the disease which could help improve its diagnosis and treatment.
Millions of people in the United States alone have submitted their DNA for analysis and received information that not only predicts their risk for disease but, it turns out, in some cases might also have influenced that risk, according to a recent study by researchers at Stanford University.
Scientists have discovered eight genes linked to red hair, helping to solve a mystery of how redheads inherit their flaming locks. The study—which also sheds light on blondes and brunettes—is the largest genetic study of hair color to date
Patients undergoing cardiac surgery are at high risk for postoperative delirium, which is associated with longer hospital and intensive care lengths of stays increased morbidity and mortality. Because sleep disturbances are common in delirium, melatonin has been an area of interest in the treatment of delirium.
It sounds too good to be true, but a novel approach that might allow you to eat as much food as you want without gaining weight could be a reality in the near future. When a single gene known as RCAN1 was removed in mice and they were fed a high-fat diet, they failed to gain weight, even after gorging on high-fat foods for prolonged periods