Research suggests that a gene that governs the body's biological (circadian) clock acts differently in evils versus females and may protect females from heart disease. The study is the first to analyze circadian blood pressure rhythms in female mice. The research, published ahead of print in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology , was chosen as an APS select article for January.
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Genes contain all the information needed for the functioning of cells, tissues, and organs in our body. Gene expression, meaning when and how are the genes being read and executed, is it regulated as an assembly line with several things happening one after another.
Most evolutionary biologists distinguish one species from another based on reproductivity: members of different species either won't or can't mate with one another, or, if they do, the resulting offspring are often sterile, unviable, or suffer some other sort of reduced fitness.
Nature has made extravagant use of a simple molecule DNA, the floorplan of all earthly life. Inventive researchers have used the same base-pairing properties that bond two strands of DNA into the familiar double helix to build innumerable useful structures at the nanometer scale.
Genetic alterations in low-risk prostate cancer diagnosed by needle biopsy can identify men that harbor higher-risk cancer in their prostate glands, researchers have discovered. The research found for the first time that genetic alterations associated with intermediate- and high-risk prostate cancer also may be present in some cases of low-risk prostate cancers.
As genomic sequencing becomes increasingly commonplace in the clinic, questions remain about its use and role among newborns. Can sequencing provide actionable insights? How common is it to find something relevant to a child's future health? What benefits or consequences will sequencing have for families?.
In the largest population genomics investigation to date, a team of researchers at the Icahn School of Medicine at Mount Sinai, Stanford University, and the University of Colorado have discovered that kidney disease risk variants of the gene APOL1, previously known to affect African and African American populations, are also found at appreciable frequencies in the Caribbean and Latin American people.
Most Americans say it would be OK to use gene-editing technology to create babies protected against a variety of diseases, but a new poll shows they'd draw the line at changing DNA, so children are born smarter, faster or taller.
Nearly half of patients with breast cancer who, on multigene panel testing, are found to have a pathogenic or likely pathogenic variant for breast cancer do not meet current National Comprehensive Cancer Network (NCCN) guidelines for genetic testing, new research shows.
DNA testing can identify a genetic culprit in about 10 % of adults with chronic kidney disease and impacts treatment for most of them.
A group of genes that have been largely ignored by scientists could play critical roles in atherosclerosis (hardening of the arteries), inflammation, and likely obesity and other metabolic diseases, new research suggests.
Researchers at the Icahn School of Medicine at Mount Sinai and The Rockefeller University have discovered the use of a long-standing computational concept known as "blacklisting," which is a form of access control, blocking unwanted files and messages .