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Medical genetics

Novel Strategy To Target Common Type Of Cancer

Researchers have identified a protein critical for the survival of a particular type of tumor cell, according to a study published today in eLife. Because The findings; originally posted on bioRxiv, suggest that targeting a protein called Werner syndrome helicase (WRN) could represent a novel opportunity for treating a subgroup of cancer patients with microsatellite instability-high…

Medical genetics

My DNA Told Me Avoid Fast Food, eat vegetables

Avoid fast food, eat vegetables and exercise. It sounds like generic health advice, but they’re tips supposedly tailored to my DNA profile. The suggestions come from 23 and me, one of the companies offering to point you toward the optimal eating and exercise habits for your genetics. As with most dieting schemes, the idea is…

Medical Genetics

Over 400 Genes Associated With Schizophrenia Development

n the largest study of its kind, involving more than 100,000 people, researchers at the Icahn School of Medicine at Mount Sinai have applied a novel machine learning method to identify 413 genetic associations with schizophrenia across 13 brain regions. As described in the February issue of Nature Genetics, examining gene expression at the tissue level…

Medical genetics

Gene Interactions Holds Key To Personalized Medicine

When the Human Genome Project was completed, in 2003, it opened the door to a radical new idea of health—that of personalized medicine, in which disease risk and appropriate treatment would be gleaned from one’s genetic makeup. As more people had their genomes sequenced; disease-related genes would start coming into view and while this is…

Medical genetics

Causative Genes Of Osteoporosis Is More Effective Treatments

Scientists have harnessed powerful data analysis tools and three dimensional studies of genomic geography to implicate new risk genes for osteoporosis, the chronic bone weakening condition that affects millions of people. Knowing the causative genes may later open the door to more effective treatments. “Identifying a disease’s actual underlying cause often helps to steer us…

Medical genetics

Genome Sequences Deduce Ancient Human Population

Australian researchers have used current hepatitis B virus (HBV) genome sequences to deduce ancient human population movements into Australia, adding weight to the theory that the mainland Aboriginal population separated from other early humans at least 59 thousand years ago and possibly entered the country near the Tiwi Islands. Molecular epidemiology The discovery is make …

Medical Genetics

Editing Genes Shouldn't Be Too Scary Unless They Are The Ones

Gene editing is one of the scarier things in the science news, but not all gene editing is the same. It matters whether researchers edit “somatic” cells or “germline” cells. Germline cells are the ones that propagate into an entire organism either cells that make sperm and eggs (known as germ cells), or the cells in…

Medical Genetics

Human Gene Editing And Designer Babies Experiments

Powerful gene editing tools could soon face a global regulations on their use on human embryos; sperms or eggs. There have been instances of outrageous use of these powerful tools on modifying the DNA of sperm; eggs or embryos that would go on to become live human beings by rogue and unethical researchers. This call…

Medical genetics

Gene Behind Mitochondrial Disease Has More Varied Effects

For more than two decades, mutations in a gene located in the DNA of mitochondria have been classified as a mitochondrial disease and linked to a particular set of symptoms. However; according to new findings from researchers at Children’s Hospital of Philadelphia (CHOP); mutations in this gene, which encodes an essential part of the mitochondrial…

Medical genetic

New Method To Boost Efficiency Of CRISPR Gene Editing In DMD

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases. The finding stemmed from research at UT Southwestern in which a single-cut gene-editing technique is use on mice and human cells to…

Medical genetics

DNA Sequencing Method Aid Development Of Anticancer Drugs

DNA is small. Really, really, small. So, when researchers want to study the structure of a single stranded DNA, they can’t just pull out their microscopes: they have to get creative. In a study published this week in Scientific Reports, researchers from Japan’s Osaka University explain how they came up with a really small solution to…

Medical antigenic

Getting Closer To A Scary 'Post Antibiotic World

The products of wastewater treatment have been found to contain trace amounts of antibiotic resistant DNA. These products are often reintroduced to the environment and water supply, potentially resulting in the spread of antibiotic resistance. As such, researchers at the University of Southern California Viterbi School of Engineering have been studying the development of these…