Medical genetics

The researches find that the The availability of faster and less expensive genetic testing; there is need for more specialize multidisciplinary clinical programs that combine focused expertise in heart disease and genetics; therefore according to a new statement from the American Heart Association; because the world’s leading voluntary organization focus on heart and brain health.

Leading voluntary organization

The statement is publish in the Association’s journal Circulation: Genomic and Precision Medicine. Cardiovascular genetics; as a sub specialty; has grown exponentially with the advances in genome sequencing and genetic testing and the growing understanding of the genetic basis of multiple heart conditions.

Challenges exist with rapid growth; including the interpretation of genetic test results and the evaluation; counseling and management of genetically at-risk family members who have inherited the genetic alteration that increases their predisposition to a certain disease even if they have not yet shown signs or symptoms.

Genetically at-risk family

Currently, there are a few broad-based cardiovascular genetics programs in existence at academic centers; as well as smaller programs focused on a specific disease; such as hypertrophic cardiomyopathy the most common genetic disorder of the heart; which results in a thickened heart muscle that has a harder time pumping blood.

Statement authors said a specialized genetic program that provides the integration of clinical cardiovascular findings – including those obtained from physical examination; imaging and functional assessment – with genetic information allows for improved diagnosis, therefore prognosis and generational family testing to identify and manage risk and in certain cases to provide genotype-specific therapy.

Specialized programs in cardiovascular genetics could benefit both those with inherited heart conditions and their healthy family members; according to the statement. “A patient who has a rare; genetic heart disease will benefit from specialized care from experts who know how to manage a disease that’s not familiar to the general cardiologist;” said Kiran Musunuru, M.D., Ph.D., M.P.H; associate professor of cardiovascular medicine and genetics at the University of Pennsylvania and outgoing editor-in-chief of Circulation:

Inherited heart conditions

“Others having a close relative with an inherited heart disease can be screen to see if they have inherited genes that put them at risk for getting the disease in the future. If so; they can be monitored over time for early signs of disease and they can; in some cases, be treated to prevent the most serious consequences of the disease.”

Ahmad said in addition to providing quality care to families; these centers will also become key places for the genetics training of internal medicine and pediatric residents and cardiology fellows. Because The American Heart Association is prepare to be part of the educational efforts needed to translate advances in genetics into better care for families with heart disease.