Biomedical scientists at the University of Salford found that sugar from the common cockle ( Cerastoderma edule ) were approximately as effective as some standard chemotherapy drugs at a relatively lower dosage.

And they say 'cockle-chemo' could be particularly suitable for children as it is potentially less toxic and less likely to cause unhealthy side-effects. Publishing in the journal Marine Drugs, the Salford team have tested the mollusk-derived sugars with positive results against leukemia , breast, lung, and colon cancer cells and tumors.

Lead researcher Dr. David Pye, Director of Child Cancer Research Charity Kidscan at the University of Salford, said: "Polysaccharides (sugars) derived from mammals have long been a source of experimentation by cancer scientists but to date with inconclusive results . actually helped cancer to grow.


"We opted to look at shellfish instead, because they are much cheaper and easier to source and well as they are rich in sugars. They have a different structure from which we are starting to derive a number of potential drugs which with further refinement have the potential to work alongside more traditional treatments, "said Pye.

He said extracting a mix of polysaccharides from cockles was a simple procedure and that the impact on tumors was encouraging. Between 2-3 out of every 10 children in Britain with cancer diagnoses will not survive to adulthood, a fact which drives research at the Kidscan labs in Salford.

"What is really significant about this is not so much the seafood source but that fact that sugars of this chemical structure work effectively at tolerable levels for children," said Pye.

"A lot of children's cancer drugs are watered down versions of adult ones, and they target and stop cell division. Clearly, as cell division is a central process of growth and development they hit children's health disproportionately," said Pye.

"The 'Holy Grail' of children's cancer chemotherapy is to maximize the destruction of cancer while minimizing damage to normal cells and tissues." Sugars as therapeutic treatments should help to minimize harmful side effects , "said Pye.