All news from Marine Medicine

Marine-Derived

Pathway From Marine-Derived Streptomyces Costaricanus

Actinomycins are a group of chromopeptide lactone antibiotics. To date, 42 actinomycins have isolated and identified from many species of Streptomyces, including actinomycin D, N-demethylactinomycins; actinomycin C, actinomycin F, actinomycin Z, actinomycin G, and actinomycin Y. Some actinomycin analogs, such as methylated actinomycin D, an actinomycin Z analog having an additional oxygen bridge between the chromophore…

Marine world

Marine Macrolides With Antibacterial And Antifungal Activity

The marine world is rich in species and very diverse. Thus marine organisms are a source of many substances with biological activity; including cytotoxic and antimicrobial. According to Burja et al., it was that in the marine world, there are over 13,000 unique compounds. Important marine groups containing biologically active substances; including macrolides are, among…

Ecosystems and fisheries

New Technology Identifies Regions Where Coral Reef Ecosystems

Researchers from the University of Hawai’i at Mānoa (UH Mānoa); the State of Hawai’i Department of Health have developed and applied a new technology in Hawai’i that identifies where coral reef ecosystems and fisheries are vulnerable to human activities and where to focus management actions to minimize anthropogenic impacts. The authors of the newly published…

Sea Resources

Prebiotics From Non-edible Forest And Sea Resources

With the help of forest residues such as sawdust, branches, and tops (GROT) and cellulose from sea squirts; researchers in Biochemical Process Engineering at Luleå University of Technology, want to make our stomach to feel better. The researchers are the first to develop prebiotics from the non-edible forest and sea resources; into a type of…

Fish Brain Cells

Fish Brain Cells React To Alzheimer's disease

Zebrafish, in contrast to humans, have outstanding regenerative capacities; If brain cells are lost due to illness or injury, they will easily regrow from so-called progenitor cells. With sophisticated methods, researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Technische Universität Dresden (TUD) have now these progenitor cells in great detail and determined…

Astaxanthin

Astaxanthin As A Peroxisome Proliferator-Activated Receptor

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptors superfamily and are ligand-transcription factors. They play an important role in the expression of many genes regulating cellular differentiation, the metabolism of glucose and lipids; carcinogenesis. Since the first PPAR was in 1990, three isoforms (PPARα, β/δ, and γ) have identified in mammalian species.…

Actinomycete Streptomyces

Activity From The Mangrove-Derived Actinomycete Streptomyces

Ansamycins are a class of bioactive macrolides that have isolated from actinomycetes. The most representatives of them are geldanamycin with HSP90 inhibitory activity, rifamycin with antibacterial activity; maytansinoid with anticancer activity. Divergolides represent a family of ansamycins with a 19-membered naphthalenic ansamacrolactam skeleton; which was first discovered from Streptomyces sp. HKI0576 and reported in 2011.…

Mycosporine

Mycosporine: Antioxidative, Anti-Inflammatory, Anti-Aging Properties

The skin, the largest human organ, is constantly exposing to the external environment. Exposure to a variety of environmental stress factors, particularly ultraviolet (UV) radiation in sunlight; can damage the skin. Sunlight can break down into three types of nonionizing electromagnetic radiation infrared (IR) (780–3000 nm); visible (400–780 nm), and UV (100–400 nm). The percentages…

Cartilage of Hoki

Major And Minor Collagens From Hyaline Cartilage of Hoki

Collagens and proteoglycans are the main proteins in the extra cellular matrix of cartilage; together with water, they give cartilage its strength and elastic properties. In human cartilage, the majority of the collagen framework is up of type II collagen; accompanied by lesser amounts of minor collagens (1%–6% of total collagen), such as type IX…

Phloroglucinol

Protective Effect Of Phloroglucinol On Oxidative Stress

Reactive oxygen species (ROS) act as important regulatory molecules of the intracellular signaling system for physiological responses. However, excessive production of ROS beyond the antioxidant capacity of cells can cause irreversible severe oxidative damage to the cells . Such damage has reported to correlate with the incidence of various diseases; such as inflammation, aging, and…

Marine sponges

Antiangiogenic Potential Of Solomonamide A Bioactive Precursors

Marine sponges are as a rich source of new potential bioactive compounds. In living sponges, these compounds are mainly secondary metabolites; whose natural functions include defense against predators and competition with other sessile species. The increasing interest for sponge-isolated compounds in biomedical and pharmaceutical research derives from the potential clinical applications exhibited by them; according…

Marine fungi

Biotechnological: Marine Fungi From The Sponge Grantia compressa

In the last few decades, antibiotic resistance significantly increased; while the discovery of new molecules suitable for the therapy of infectious diseases slowed down; therefore, finding new antimicrobial compounds became a priority. Natural products of terrestrial origins are the primary sources of bioactive molecules. However, unexplored environments and organisms, such as those inhabiting the sea;…