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Immune Haematology

Angiotensin Receptor Blockers Response to Cancer Immunotherapy

A research team led by investigators at Massachusetts General Hospital (MGH) and the Massachusetts Institute of Technology (MIT) has found that combining a specialized version of an antihypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies. As described in their report published in PNAS; the combination treatment significantly improved tumor response and survival…

Immune haematology

Angiotensin Blockers Response to Cancer Immunotherapy

A research team led by investigators at Massachusetts General Hospital (MGH) and the Massachusetts Institute of Technology (MIT) has found that combining a specialized version of an anti hypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies.  As described in their report published in PNAS; the combination treatment significantly improved tumor response…

Immune hematology

Causal Associations for 47 Adverse Effects After Immunization

A new systematic review provides a succinct summary of the scientific evidence for and/or against causal associations for 47 adverse events following immunization (AEFI). Findings from the study is present during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24 – May 1 in Baltimore. “Health care providers desire objective and clear…

Immune haematology

New Device Makes Encapsulating Cells Much Faster

A simple injection that can help regrow damaged tissue has long been the dream of physicians and patients alike. A new study from researchers at UBC Okanagan moves that dream closer to reality with a device that makes encapsulating cells much faster; cheaper and more effective. “The idea of injecting different kinds of tissue cells…

Immune hematology

Vitamin D Study Sheds Light on Immune System Effects

Scientists have uncovered fresh insights into how vitamin D affects the immune system and might influence susceptibility to diseases such as multiple sclerosis. Vitamin D is produced by the body in response to sunlight and is often lauded for its health benefits. Researchers found it also affects key cells of the immune system. Response to…

Immunehaematology

Restores Immunity in Infants With Rare Immunodeficiency Disease

A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting immune cells do not develop or function normally. therefore Eight infants with the disorder; called X-linked severe combined immunodeficiency (X-SCID), received an experimental gene therapy co-developed by…

Immune hematology

Women Get Autoimmune Diseases Far More Often Than Men

It’s one of the great mysteries of medicine, and one that affects the lives of millions of people: Why do women’s immune systems gang up on them far more than men’s do, causing nine times more women to develop autoimmune diseases such as lupus Part of the answer, it turns out, may lie in the…

Immune haematology

Oral Immunotherapy Safe for Preschool-Aged Children

New data published this week in the Journal of Allergy and Clinical Immunology: In Practice suggests that oral immunotherapy is safe for preschool-aged children with peanut allergies. The research; led by scientists and pediatric allergists at the University of British Columbia and BC Children’s Hospital, is the first to demonstrate the safety of peanut oral immunotherapy…

Immune haematology

Innate Immune Sensor Responding to Gut Microbes

UT Southwestern researchers have found that a protein in the body’s innate immune system that responds to gut microbes can suppress the most common type of liver cancer. Therefore  The study, published today in the journal eLife, determined that NLRP12, an innate immune sensor, has a protective effect against hepatocellular carcinoma (HCC), a deadly human…

Immune hematology

Recurrent strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcustonsillitis (“strep throat”); researchers report. Recurrent tonsillitis is a common indication for tonsillectomy, yet it remains unclear why some children get group A Streptococcus (GAS) recurrent tonsillitis and others do not. Dr. Shane Crotty from La Jolla Institute for Immunology and the University…

Immune haematology

Immune Responses in Ebola Survivors 2 Years After Infection

Scientists have discovered that 2 years after infection, West African Ebola survivors exhibit memory immune responses including specific T cells against Ebola virus. They believe their discovery opens up the possibility of improving Ebola vaccines by boosting key immune cells needed for long-lasting protective immunity. Therefore The new research is being presented at this year’s…

Immune haematology

Antibodies Help CAR T-cell Therapies to Kill Solid Tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. It is a miniaturize version of a human antibody, made up only of two heavy protein chains, rather than two light and two heavy chains. As…