The goal of this nano immunotherapy combination is to increase the potency of immune checkpoint inhibitors, a class of immunotherapy that elicits dramatic benefits in only a modest subset of cancer patients, to a significantly larger proportion of patients. because A team from the George Washington University (GW) Cancer Center has engineered nano immunotherapy that…
Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma (GBM) progression by shutting down immune surveillance; indicating a potential new area of therapeutic investigation. Findings from the preclinical study lid by Shulin Li, Ph.D., professor of Pediatrics; and Amy Heimberger, M.D., professor of Neurosurgery;…
researchers have known that normal bacteria in the gut can induce intestinal immune cells to extend tentacle-like structures, known as dendrites, to “capture” antigens; triggering both immediate and long-term immune responses. What was less clear was how the bacteria activate this process. Now, a research team led by Osaka University has found that the molecules…
Immunotherapy a promising treatment for peanut allergies uncomfortable side effects can induce anxiety. young patients to the mindset that so uncomfortable side effects are a sign that treatment is working can help reduce anxiety, according to new research by Stanford psychologists. The study, published Jan. 28 in Journal of Allergy and Clinical Immunology In Practice,…
For at least a decade, researchers have known that normal bacteria in the gut can induce intestinal immune cells to extend tentacle-like structures, known as dendrites, to "capture" antigens, triggering both immediate and long-term immune responses.
A Ludwig Cancer Research study has uncovered a cellular mechanism by which melanomas that fail to respond to checkpoint blockade may be made susceptible to such immunotherapies. the study also identifies an existing diabetes drug that could be used to accomplish that feat.
Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. The scientists at the Abramson Cancer Center of the University have identified how to fuel macrophages with the energy needed to attack and eat cancer cells.
White blood cells, also known as monocytes, play a key role in the immune system's response to infection. They have been shown to fuse and form multinucleated giant cells (MGCs) during inflammatory reactions, or in response to introduced materials such as medical implants, but little is known about the mechanisms underlying the fusion process and its functional significance.
Checkpoint inhibitor therapy is a form of cancer treatment immunotherapy currently under research. The therapy targets immune checkpoints, key regulators of the immune system that stimulate or inhibit its actions, which tumors can use to protect themselves from attacks by the immune system.
A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells which can give rise to every cell type in the body and which can be grown indefinitely in the lab into becoming mature T cells capable of killing tumor cells.
Chaos in bodily regulation can optimize our immune system according to a recent discovery made by researchers at the University of Copenhagen's Niels Bohr Institute. The discovery may prove to be of great significance for avoiding serious diseases such as cancer and diabetes.
Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how. They found in mice that fever alters surface proteins on immune cells like lymphocytes to make them better able to travel via blood vessels to reach the site of infection.