Immune hematology

The Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases (NIAID) to fund the IGS Genome Center for Infectious Diseases (GCID) for another five years. Because The Principal Investigator and Administrative Core Director for the grant, which is titled.  Because “A Genomics Based Investigation of the Determinants of Polymicrobial Infectious Disease Outcomes,” is David Rasko, PhD, Professor of Microbiology and Immunology and Scientist at IGS.

Bioinformatics

Team investigators will include: Claire M. Fraser, PhD, the Dean’s Endowed Professor of Medicine, Microbiology and Immunology, and Director of IGS, and Owen R. White, PhD, Professor of Epidemiology and Public Health, Director of Bioinformatics and Associate Director of IGS.,

The GCID uses large-scale genomics and bioinformatics approaches to investigate pathogen biology, virulence, immune evasion, microbe-microbe interactions as well as host-microbiome interactions. Because Scientific research projects focus on host/microbe interrelationships of diverse bacteria, fungi, and parasites.

Because The interdisciplinary team will participate in the GCID research; therefore  including internationally recognized faculty from the Institute for Genome Sciences; the Department of Microbiology and Immunology and the UMSOM Center for Vaccine Development and Global Health (CVD) and their long-standing collaborators.

Applying genomic

“The GCID team has been in the forefront of applying genomic techniques to advance scientific understanding of infectious disease agents for the past 15 years; and this NIAID grant renewal will allow us to further deploy genomics approaches in the study of host-pathogen-microbiome interactions,” said Dr. Fraser.

The NIAID grant will support research programs that focus on three areas. One research area involves studying the interactions of multiple bacteria with each other as well as the host and associated microbiome; therefore which is led by Dr. Rasko, Dr. Fraser; and Herve S.G. Tettelin, PhD, Associate Professor of Microbiology and Immunology and Scientist at IGS. The second area includes research into the genomic and transcriptomic analysis of fungal pathogens interacting with the host; which will be led by Vincent M. Bruno, PhD, Associate Professor of Microbiology and Immunology and Scientist at IGS.

Microbiology and Immunology

The third area of research includes an integrated genomics research project in parasitic tropical diseases that will be led by Julie C. Dunning Hotopp, PhD, Associate Professor of Microbiology and Immunology and Scientist at IGS, David Serre, PhD; Associate Professor of Microbiology and Immunology and Scientist at IGS; and Joana C. Silva, PhD, Associate Professor of Microbiology and Immunology and Scientist at