Immune hematology

The study find that the a little dirty  with farm animals just might help us fend off illness; say researchers who’ve further demonstrated the benefits of early exposure to a wide variety of environmental bacteria. Therefore Scientists from The Ohio State University found that bacteria and other microbes from rural Amish babies was far more diverse in a beneficial way – than what was found in urban babies’ intestines. And, in a first-of-its-kind experiment; they found evidence of how a healthier gut microbiome might lead to more robust development of the respiratory immune system.

Respiratory immune system

The study is publish this month in the journal Frontiers in Immunology. Good hygiene is important, but from the perspective of our immune systems, a sanitized environment robs our immune systems of the opportunity to be educate by microbes. Too clean is not necessarily a good thing.Because ” Study’s co-lead author Zhongtang Yu; professor of microbiology, Ohio State’s Department of Animal Sciences and member of the university’s Food Innovation Center

The research team collected fecal samples from 10 Ohio babies who were around 6 months to a year old. The five Amish babies all lived in rural homes with farm animals. But The other five babies lived in or near Wooster; a midsize Ohio city; and had no known contact with livestock. The samples reveal important differences particularly a wide variation in microbes and an abundance of beneficial bacteria in the Amish babies’ guts that are not find in their city-dwelling counterparts.

Abundance of beneficial bacteria

The researchers expected this, based on the infants’ exposure to the livestock and the fact that the Amish tend to live a relatively less-sanitized lifestyle than most other Americans. “The priming of the early immune system is much different in Amish babies; compared to city dwellers;” said Renukaradhya Gourapura, co-lead author of the study and a professor in Ohio State’s College of Food; Agricultural and Environmental Sciences and Food Animal Health Research Program.

What they really want to know was how these differences might affect development of the immune system; setting the groundwork for a body’s ability to identify and attack diseases and its resistance to allergies and other immune-system problems. Therefore Previous studies in the U.S. Amish population and to comparable populations throughout the world have drawn a clear connection between rural life and a decrease in allergies and asthma; Gourapura says.

This connection has led to a theory call the “hygiene hypothesis;” which is built on the idea that hyper-clean modern life – think antibacterial soap, ubiquitous hand sanitizer and scrubbed-clean homes and workplaces has led to an increase in autoimmune and allergic diseases.