Nine-year-old Hannah Day has once again been diagnosed with acute lymphoblastic leukemia a type of cancer that affects the blood and bone marrow. However, “her bone marrow is negative and her blood shows no signs of ALL [acute lymphoblastic leukemia],” reads the report. It turns out the rare twists and turns that have marked the…
NHS bosses are reviewing the Southend stroke unit’s thrombectomy service where blood clots which have caused strokes are removed from vessels in the brain and could move it to Basildon Hospital. The Mid and South Essex Sustainability and Transformation Partnership came up with plans to share services and staff between Southend; Basildon and Broomfield Hospital…
The best way to do this, of course, would be a time machine. But failing that, Späth had the next best thing: frozen blood samples from years before from three different biobanks. By using blood samples taken from individuals years previously, Späth was able to compare blood from people who had subsequently developed cancer to…
When Lincoln Maziasz was diagnosed with leukemia shortly after his fourth birthday, it was hard for his parents, Katie and Drew, to come to terms with. There were the logistics of treatment protocol. Especially in a family with two other young children: Carter, who was 6 at the time, and Layne, who was 1 at…
Acute promyelocytic leukaemia (APL), an aggressive subtype of acute myeloid leukaemia (AML), a type of blood cancer, is characterised by an increment in the number of immature blood-forming cells (promyelocytes) present in blood and bone marrow. The accumulation of promyelocytes drives to a deficiency in normal white and red blood cells and platelets in the…
When we have small wounds on our skin or muscles they can usually heal by themselves. But in deeper wounds such as those in diabetic patients or in muscle tissue after a heart attack repair is more difficult. These sorts of issues often require more serious treatments, and may eventually need amputation or a transplant…
When organs or tissues are damaged, new blood vessels must form as they play a vital role in bringing nutrients and eliminating waste. This is the only way for organs and tissues to resume their normal function. At present, the injection of growth factors or genetic material into the tissue site of interest can trigger…
Researchers at the University of Sydney have used biomechanical engineering techniques to unlock the mystery surrounding the mechanical forces that influence blood clotting. Because The findings take researchers one step closer to developing new anti-thrombotic drugs without the serious side effects that cause fatal bleeding. While coagulation the activation of platelets clumping together is key…
A study at The University of Texas MD Anderson Cancer Center revealed the investigational drug umbralisib as an effective treatment for patients with relapsed marginal zone lymphoma (MZL). Findings from the Phase II trial were presented by study co-lead Nathan Fowler, M.D., associate professor in the Department of Lymphoma & Myeloma, at the AACR Annual…
A prototype wearable device, tested in animal models, can continuously collect live cancer cells directly from a patient’s blood. Developed by a team of engineers and doctors at the University of Michigan; it could help doctors diagnose and treat cancer more effectively. “Nobody wants to have a biopsy. If we could get enough cancer cells from the…
Acute erythroid leukemia (AEL) is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children’s Research Hospital that appears today in the journal Nature Genetics. The researchers completed the largest, most comprehensive genomic analysis yet of AEL and identified six…
Researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases sickle cell disease and beta thalassemia applying CRISPR-Cas9 gene editing to patients’ own blood stem cells. Described this week in Nature Medicine and in a…