All news from Hematology & Oncology

Haematology

Discontinuing TKI Therapy for Chronic Myeloid Leukemia

Although discontinuation of tyrosine kinase inhibitor (TKI) therapy is an option for select patients with chronic phase chronic myeloid leukemia (CML), a study designed to assess patient attitudes regarding this option showed varying results and misunderstandings of the risks and benefits of this approach. The findings of this study is publish in The Oncologist. Misunderstandings of…

Haematology

Devon Air Ambulance to Carry Blood Plasma

Devon’s Air Ambulance can now provide additional life saving treatment. The crew will now be carrying LyoPlas – a part of the blood which helps it to clot.  Nigel Hare, Operations Director for Devon Air Ambulance explains “In simple terms, blood is made up of red blood cells which carry oxygen around the body; white…

Haematology

Drug Combo may Prove Effective Against Second Type of Leukemia

Every year, nearly 11,000 Americans die of acute myeloid leukemia (AML), a blood cancer that affects mainly older adults. While most patients initially respond to chemotherapy; more than half of those who respond will eventually relapse as the cancer cells develop resistance to treatment. Respond to chemotherapy In a new paper published today in Cell Research,…

Haematology

White Blood Cells in Antiphospholipid Syndrome Reduced Blood Clots

For men and women affected with antiphospholipid syndrome (APS), blood thinners are the main treatment option. “Unfortunately, treatment with blood thinners does not prevent all cases of blood clotting in APS,” says Jason Knight, M.D., Ph.D., an assistant professor of rheumatology at Michigan Medicine. APS is an autoimmune condition characterized by blood clots in both genders and…

Transfusion medicine

Blood Thinner Found to Reduce Subsequent Heart Failure Risks

Researchers at University of California San Diego School of Medicine found that using blood thinners in patients with worsening heart failure; coronary artery disease or irregular heart rhythms was associated with a 17% reduced risk of thromboembolic events; such as stroke and heart attack. Congestive heart failure Results from the COMMANDER Heart Failure trial are…

Beta-Thalassemia

The Efficacy And Cost Of Curative Gene Therapy For Beta-Thalassemia

Gene therapy offers the promise of a cure for beta-thalassemia and a new study has shown that it is associated; with fewer complications and hospital admissions over 2 years than treatment; allogeneic hematopoietic stem cell transplantation (HSCT). The study, which analyzes and compares the effectiveness and cost of gene therapy versus (HSCT) in patients; with…

molecular machine in cell nucleus

Key to Treating Aggressive Leukemia: Molecular Machine in Nucleus

Many individuals forced to fight an exceptionally aggressive form of the blood cancer acute myeloid leukemia (AML) don’t survive more than five years. The only cure — a bone marrow transplant — often isn’t suitable for these very sick patients. Now, an international team of scientists report in Nature Cell Biology on a long-overlooked part of…

Haematology

Leukemia Cells Become Resistant to Drugs

Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children’s Hospital still haunt him more than a decade later. One 15-year-old boy died from the toxicity of the drugs he was given; the other two patients went through the whole treatment only to die when their leukemia came back. “That really…

Hematology

Coagulation Factor VIIa Prevents Bleeds in Hemophilia

Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well. A study in animals may set the stage for a new therapy for a subset of patients with hemophilia who now develop antibodies to the standard maintenance…

Haematology

Presence of Leukemia Cutis Tied to Worse Survival in AML

For patients with acute myeloid leukemia (AML), the presence of leukemia cutis (LC) is associated with decreased overall and leukemia-specific survival, according to a study published online  in JAMA Dermatology. Cynthia X. Wang, M.P.H.S., from Washington University School of Medicine in St. Louis, and colleagues conducted a retrospective cohort study involving 1,683 patients with AML with and…