All news from Hematology & Oncology

Stem Cell Therapy Improve Fight Against Leukemia

Stem cell transplantation is effective against leukemia. In many cases, however, the transferred immune cells of the donor also attack the recipients' healthy tissue—often with fatal consequences. Researchers at the University of Zurich have now identified a molecule that plays a key role in this process.

Oncology Drug For Key Genetic Driver of Cancer

The U.S. Food and Drug Administration today granted accelerated approval to Vitrakvi (larotrectinib), a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker). This is the second time the agency has approved a cancer treatment based on a common biomarker across different types of tumors rather than the location in the body where the tumor originated.

Challenges In Treating Severe Pain of Sickle Cell Disease

In a study tracking the severe crisis pain of sickle cell disease and its management in 73 adults over a period of a year, Johns Hopkins researchers found that even among those on high doses of daily at-home opioids, a persistent subset was more likely to seek emergency hospital care for crisis pain and was less likely to have the pain controlled by intensive treatment.

New Antibody Immunotherapy Fights Against Cancer

Scientists at the University of Southampton have developed a new antibody that could hold the key to unlocking cancer's defence against the body's immune system. In a new study published in Immunity, the team, which is based at the Centre for Cancer Immunology, engineered antibodies to target a particularly significant immune receptor called 4-1BB, which can activate killer T-cells to find and destroy cancer cells.