All news from Hematology & Oncology

Blood cancer

Premature Aging In The Bone Marrow: Leukemia Promotes

Acute leukemia develops quickly and worsens rapidly Leukemia is a cancer of the blood or bone marrow. Bone marrow produces blood cells. Leukemia can happen when there is a problem with the production of blood cells. It usually affects the leukocytes, or white blood cells. It is most likely to affect people over the age of 55…

Blood cancer

AICAr Drug: Molecular Mechanisms Behind It

AICAr (5-amino-4-imidazolecarboxamide riboside; also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug’s cytotoxic mechanisms; however, remain unknown. A new study published in The FASEB Journalexplores the mechanisms behind AICAr. Specifically, the study was to determine; 1) whether AMP-activated protein kinase (AMPK) was…

Blood cancer

Next-generation Treatment: For Aggressive Form Of Leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML); an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year; and about 10,670 people a year die from it, according to the American Cancer…

Blood cancer

Epigenetic Changes In Leukemia Cells: New Approach Identifies

Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy for chronic lymphocytic leukemia first approved in 2014. Chronic lymphocytic leukemia, caused by uncontrolled growth of cells from the body’s immune system. It is the most common leukemia in the Western world. Most…

Many Hepatitis Infections Go Undiagnosed In Cancer Patients

Results from the largest study of hepatitis B and C and HIV infection prevalence in cancer patients show an alarmingly high rate of undiagnosed acute and chronic hepatitis B and C.

Hepatitis B and C are serious but treatable viral infections that cancer patients should know they have—because these viruses can cause life-threatening complications when certain cancer treatments are used.

FDA Approves New Enzyme Product for ALL

The US Food and Drug Administration (FDA) has approved a new drug for the treatment of acute lymphoblastic leukemia (ALL), a cancer of the blood and bone marrow. 

The agency has granted approval for calaspargase pegol-mknl (Asparlas, Servier Pharmaceuticals), an asparagine-specific enzyme, to be used as part of a multi-agent chemotherapeutic regimen in pediatric and young adult patients (age 1 month to 21 years).