The researches find that the use of Mohs surgery for melanoma increased more than threefold, according to a study published online Aug. 28 in JAMA Dermatology. Michael P. Lee; from Eastern Virginia Medical School in Norfolk; and colleagues conducted a national cross-sectional analysis involving 79,108 patients undergoing surgical excision for melanoma from Jan. 1, 2001, through Dec. 31, 2016. The likelihood of a melanoma being treat with Mohs surgery was examined over time.
The surgery for melanoma
Melanoma (pronounced /ˌmɛləˈnoʊmə/ ( listen)) is a malignant tumor of melanocytes which are find predominantly in skin but also in the bowel and the eye (see uveal melanoma). But It is one of the less common types of skin cancer but causes the majority of skin cancer related deaths. Malignant melanoma is a serious type of skin cancer. It is due to uncontrolled growth of pigment cells; called melanocytes. Despite many years of intensive laboratory and clinical research; the sole effective cure is surgical resection of the primary tumor before it achieves a Breslow thickness greater than 1 mm.
Around 160,000 new cases of melanoma are diagnosed nationally each year; and it is more frequent in males and Caucasians. It is more common in Caucasian populations living in sunny climates than in other groups. According to a WHO report about 48;000 melanoma related deaths occur worldwide per year. The researchers found that 75,047 patients were treated with conventional surgery and 4,061 were treated with Mohs surgery.
Common types of skin cancer
Mohs surgery is use in 5.1% of all surgical cases and increase 304% from 2.06 to 7.9% from 2001 to 2016. In more recent calendar years, the odds of receiving Mohs surgery for melanoma increased significantly (odds ratio, 1.02 per calendar year). In 1,087 cases (26.8%), immunohistochemistry use is code with Mohs surgery; more recently; the odds of receiving Mohs surgery with immunohistochemistry increased (odds ratio, 1.13 per calendar year).
For every period, there was considerable geographic variation, with more than threefold variation between the regions with highest and lowest use of Mohs surgery and Mohs surgery with immunohistochemistry. Therefore Malignant melanoma accounts for 75 percent of all deaths associated with skin cancer. The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. “Despite stable guidelines and no randomized clinical trial data evaluating outcomes of comprehensive margin assessment surgery for melanoma, surgical excision practices for melanoma continue to evolve,” the authors write.