General surgery

The researches find that the all health care providers are fully adherent to surgical guidelines for risk-reducing salpingo-oophorectomy, according to a study publish online Annelise M. Wilhite, M.D., from the University of Minnesota in Minneapolis; and colleagues retrospectively evaluated health care ;provider adherence to the surgical protocol endorse by the National Comprehensive Cancer Network and the American College of Obstetricians and Gynecologists for risk-reducing salpingo-oophorectomy due to a pathogenic BRCA mutation (2011 to 2017).

Adherent to surgical guidelines

Adherence included collection of washings, complete resection of the fallopian tube; and performing the Sectioning and Extensively Examining the Fimbriated End (SEE-FIM) pathologic protocol. Surgeries were performed at 10 different hospitals in a single metropolitan area. The researchers found that 199 of 290 cases (69%); were adherent to the surgical protocol. Compared with obstetrician-gynecologists, gynecologic oncologists were more than twice as likely to fully adhere to the full surgical protocol (91 versus 41%).

Within the protocol, gynecologic oncologists were more likely to resect the entire tube (99 versus 95%), to have followed the SEE-FIM protocol (98 versus 82%); and collect washings (94 versus 49%). Complication rates were similar regardless of provider. Because The incidence of occult neoplasia was higher in gynecologic oncology patients versus obstetrics and gynecology patients (6.3 versus 0.8 percent).

Health care provider

“Rates of risk-reducing surgery will likely continue to increase as genetic testing becomes more widespread, highlighting the importance of health care provider education for this procedure;” the authors write. Genetic testing allows the genetic diagnosis of vulnerabilities to inherit diseases; and can also be use to determine a person’s ancestry. Therefor  Normally, every person carries two copies of every gene; one inherited from their mother, one inherited from their father.

The human genome is believed to contain around 20,000 – 25,000 genes. In addition to studying chromosomes to the level of individual genes, genetic testing in a broader sense includes biochemical tests for the possible presence of genetic diseases; or mutant forms of genes associated with increased risk of developing genetic disorders. Genetic testing identifies changes in chromosomes, genes, or proteins.

Includes biochemical tests

Most of the time, testing is use to find changes that are associate with inherit disorders. But The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person’s chance of developing or passing on a genetic disorder. Therefore Several hundred genetic tests are currently in use; and more are being developed. Since genetic testing may open up ethical or psychological problems, genetic testing is often accompanied by genetic counseling.