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Gastroenterology

Irritable Bowel Syndrome Offers Free Relief to Patients

A new large clinical trial “RELIEVE-IBS-D” for patients with irritable bowel syndrome causing diarrhoea is open to recruitment. The national trial, being led by experts in Newcastle, is currently recruiting over 400 patients aged between 18 and 75 years, with the key aim of showing the effectiveness of a new oral drug Enterosgel in the…

Gastroenterology

New Cell Model of Aging Associated Colon Cancer Risk

Johns Hopkins Kimmel Cancer Center researchers say a new study of clusters of mouse cells known as “organoids” has significantly strengthened evidence that epigenetic changes; common to aging, play a essential role in colon cancer initiation. The findings show that epigenetic changes are the spark that pushes colon-cancer driving gene mutations into action, the researchers…

Gastroenterology

Researchers Discover Pathway Contributing to Fatty Liver Disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications. Analysis of liver biopsies of patients indicate that the identified mechanisms may help explain the differential susceptibility of individual patients to develop more severe stages of…

Gastroenterology

Cure Hepatitis B, a Neglected Disease

A coalition of researchers, health organisations and patient groups on Wednesday launched an ambitious campaign to cure hepatitis B, a disease that kills twice as many people as malaria but gets far less attention. “Inexplicably, despite the huge human and economic toll of chronic hepatitis B (HBV), research remains largely underfunded;” said Peter Revill, a…

Gastroenterology

Blood Based Test for Colon Cancer Shows Promise

If caught early, nearly all cases of colon cancer are curable. Though this should make screening tests straightforward, colon cancer screening suffers from a paradoxical combination of low compliance rates and over diagnosis. In a study published April 8, 2019 in the Proceedings of the National Academy of Sciences, a group of University of Wisconsin Madison…

Gastroenterology

Intestinal Helminths Boost Fat Burning

Intestinal infection with helminths a class of worm-like parasites prevented weight gain in laboratory mice on a high-fat diet. The helminths did so by boosting populations of bacteria that produce compounds that trigger increased energy consumption in the mice. The research is published in Infection and Immunity, a journal of the American Society for Microbiology.…

Gastroenterology

Liver Offers Improve Transplant Survival in Patients

Patients with hepatocellular carcinoma who had a potential live donor at listing for liver transplantation had a significantly lower risk for mortality compared with those who waited for a deceased donor graft; according to recently published data. According to Nicolas Goldaracena, MD, from the University of Toronto in Canada; and colleagues, the benefits derived from…

Gastroenterology

Medical Costs for GERD and Other Health Problems

Treatment with Ethicon’s LINX Reflux Management System reduced medical costs more than laparoscopic Nissen fundoplication (LNF), a more invasive anti-reflux surgery; and more than offsets the slightly higher cost of the procedure, according to a new study presented here today at the 2019 Annual Meeting of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES…

Gastroenterology

FDA OKs Reintroduction of Tegaserod for IBS-C in Women

he US Food and Drug Administration (FDA) has approved the reintroduction of tegaserod oral tablets (Zelnorm; Sloan Pharma) for irritable bowel syndrome with constipation (IBS-C) in women younger than age 65; therefore US WorldMeds Holdings has announced. “They are excited about what the reintroduction of Zelnorm means for patients suffering from irritable bowel syndrome with constipation. Treatment…

Gastroenterology

New Therapeutic Strategy To Prevent Gastrointestinal Disease

Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier that critical lining of cells in the gut that must allow nutrients into the body while keeping food-borne microbes out can be compromised during intestinal inflammation…

Gastroenterology

Colorecal Cancer commonly misdiagnosed in patients under 50

Despite deaths from colorectal cancer cases falling significantly in the past decade, the disease remains the second leading cause of cancer-related deaths in the US. This may be due to a sharp increase of colorectal cancer diagnoses in young adults aged 20 to 49 years old. Dr. Ronit Yarden, PhD, MHSA, the study’s lead author…

Gastroenterology

Gastrointestinal Complaints In Children

A Columbia University study has found that adversity early in life is associated with increased gastrointestinal symptoms in children that may have an impact on the brain and behavior as they grow to maturity. The study was published online March 28 in the journal Development and Psychopathology. “One common reason children show up at doctors’ offices…