A first of its kind study using family base genetic analysis has confirm a gene involved in male hormone production, DENND1A, plays a major role in the development of polycystic ovary syndrome (PCOS). The discovery will enable personalize medicine approaches to PCOS, including better disease prediction. The findings are available online in The Journal of…
Women with early, low risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment; so according to results from a trial that has follow 869 women for ten years. New findings from the 8 A trial of the Austrian Breast…
Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas. The study from the Wellcome Sanger Institute, the University of Exeter and collaborators also identify a previously unexpect pathway involve in the development of the human pancreas, and confirm. Publish today (18th April)…
Administration of the EGLN inhibitor FG-4592 prior to ablative radiotherapy provided protection against fatal gastrointestinal bleeding and improved survival in a mouse model of unresectable pancreatic cancer. Journal in Which the Study was Published: Cancer Research, a journal of the American Association for Cancer Research Author: Cullen Taniguchi, MD, PhD, assistant professor of radiation oncology at…
In most cases, the cause of thyroid cancer is unknown, according to Dr. David Goldenberg, chief of otolaryngology head and neck surgery at Penn State Health. But for years, the vast majority of his thyroid cancer patients have told him they blame the 1979 partial meltdown of a reactor at Three Mile Island near Middletown,…
Patients with overt and even subclinical hypothyroidism show reductions in energy expenditure that can affect sensitivity to cold, but successful treatment to normalize thyroid hormone levels reverses the overriding process of cold-induced thermogenesis, new research shows. They speculate that hypothyroidism limits the adaptation to environmental cold exposure in humans,” say Claudia Irene Maushart; hence University Hospital Basel,…
The two main sex hormones estrogen and testosterone have wide-ranging effects in the body. Produced primarily by the ovaries (estrogen) and testes (testosterone); these hormones affect not just your sexual function but also your bones, brain, and blood vessels, for example. As people age, the natural decline in sex hormone levels sometimes causes undesirable symptoms;…
Treating breast tumors with two cancer drugs simultaneously may prevent endocrine resistance by attacking the disease along two separate gene pathways, scientists at the University of Illinois found in a new study. The two drugs use in the study; so selinexor and 4-OHT, caused the cancer cells to die and tumors to regress for prolong periods;…
Chemists at Tokyo Tech’s Laboratory for Chemistry and Life Science have design and developed a capsule-shaped synthetic receptor that can distinguish between male and female steroid hormones. Namely, the receptor displays unusual high binding affinity toward androgenic male hormones in water. Natural biological receptors Published today in Science Advances, their achievement is a prime example of…
Leonardo da Vinci’s world-renowned “Mona Lisa” painting of Lisa Gherardini has captivate millions since it was create in the early 1500s, including experts in the medical community. For years, scientists and physicians have studied the discoloration of Gherardini’s skin; so the thickness of her neck, and her enigmatic smile to hypothesize about her health during…
Nearly 20 percent of children and adolescents and 14 percent of toddlers in the United States are obese. One contributing factor, among many possibilities, may be what a baby eats during their critical first six months of life and how it affects their continued growth. Ideally, breast milk is their only food during this critical…
A modified form of the alpha-synuclein protein can be found in the salivary gland tissue of Parkinson’s patients even in the early stages of the disease, suggesting the protein could be a potential biomarker for this neuro degenerative disorder, a study reports. The study, “Nitrated alpha-synuclein in minor salivary gland biopsies in Parkinson’s disease. Peripheral autonomic nervous…