All news from Endocrinology

Combination Therapy Effective Against Aggressive Form of Thyroid Cancer

The U.S. Food and Drug Administration approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body (metastatic), and has a type of abnormal gene, BRAF V600E (BRAF V600E mutation-positive).

Intestinal Bacteria Can Affect The Blood Sugar And Lipid Levels

The researcher analyzed the influence of changes in intestinal bacteria on sugar and lipid metabolism, they have found that secondary bile acids produced by the bacteria, which can influence blood glucose and lipid concentrations as well as parts of their molecular mechanisms. Intestinal bacteria have attracted recent attention since they were discovered to influence various physiological functions and diseases in humans. The treatment of metabolic diseases such as diabetes and dyslipidemia by targeting intestinal bacteria that produce secondary bile acid.

Dyslipidemia and Hyperglycemia Evaluated in Type 1 Diabetes Mellitus

Dyslipidemia is a preventable risk factor for CVD. Screening for dyslipidemia should be performed soon after diagnosis when diabetes has stabilized in all children with T1DM aged > 10 year and if normal results are obtained, this should be repeated every 5 year.

If there is a family history of hypercholesterolemia, early CVD or if the family history is unknown, screening should commence as early as 2 year of age.

Diabetes Medicines in India: Experts Call for Action

India has one of the highest rates of type 2 diabetes in the world, and there is now "growing national and international concern" about the drug regulatory system there, which allows use of a drug treatment that has not been shown effective or safe, say researchers at the University of Massachusetts Amherst and the U.K.'s Newcastle University in a paper published today in the British Medical Journal.

Insights About Women's Hormonal Cycles

Women's hormones contain a hidden "intelligence" that women can use to make the best decisions in their lives — decisions that will help them to choose mates, avoid danger, compete with female rivals and produce healthy children, said Haselton, a UCLA professor of psychology and communication studies.

Kidney disease: Study shows it increases the risk of diabetes

Diabetes is known to increase a person's risk of kidney disease. Now, a new study suggests that the converse also is true: kidney dysfunction increases the risk of diabetes. Further, the researchers deduced that a likely culprit of the two-way relationship between kidney disease and diabetes is urea. The findings are significant because urea levels can be lowered through medication and diet.The epidemiological study, conducted in collaboration with the Veterans Affairs St. Louis Health Care System, is published in Kidney International.

Stem cells: A new way of diabetes treatment

Diabetes afflicts 415 million people worldwide, and the numbers continue to rise. A new study showed how insulin-producing cells could be produced by using human stem cells that could in the future be transplanted into diabetic patients.