All news from Endocrinology

Examine To Clarify The Onset Of Diabetes

Individuals who develop diabetes or prediabetes have elevated plasma glucose fasting (FPG) at least 10 years before diagnosis. The study was published in the Journal of the Endocrine Society.

Researchers analyzed data from 27,392 health exams without diabetes for a mean of 5.3 years. Ten years before diagnosis of prediabetes (4,781 participants) or diabetes (1,061 participants), trajectories of FPG,  body mass index  (BMI), and single point insulin sensitivity estimator (SPISE), an index of insulin sensitivity, were assessed.

Heart Failure Risk In ALVSD Patients With Diabetes

Men with diabetes are 2.4 times more likely than non-diabetics to suffer heart failure and women are five times more likely. A new Loyola University Chicago Stritch School of Medicine study reveals how, on a cellular level, diabetes can cause heart failure.

The findings could lead to medications to treat and perhaps prevent heart failure in diabetes patients . The study was published in the journal  JCI Insight . 

Diabetic Patients Die From Alcohol-Related Factors/Accidents

Diabetic patients are more likely to die from alcohol-related factors, accidents or suicide. The study was published in the  European Journal Endocrinology. The study findings suggest that the increased risk of death from these causes may be related to the mental health of patients, which may be adversely affected by the psychological burden of living with and self-treating this debilitating disease, with powerful and certain disorders.

Diabetes Type 1 And Type 2 Adult Vaccination

Diabetes reduces the immune system's ability to fight certain infections. This raises the risk of dangerous diseases from vaccines to protect against-including flu, pneumonia, hepatitis B, tetanus and shingles.

People with diabetes may be at higher risk of getting certain diseases and also serious problems from diseases that could have been prevented with vaccines. Everyone should know what vaccines they need to protect themselves and discuss with their doctor if they are up to date with the vaccines.

Serum Prolactin In Pregnancy Predicts Prediabetes

Researchers found that women with the highest levels of the hormone, although still in the normal range, had a 27% reduced risk of developing type 2 diabetes compared to those with the lowest levels in the normal range.

Prolactin is a multi-function hormone-it is not only related to pregnancy and breastfeeding, but it also plays an important role in many other biological functions, like metabolism, immune regulation, and water balance. The study was published in the Diabetologia.

Impact of Gastric Banding vs Metformin on ?-Cell Function in Adults With Impaired Glucose Tolerance

People with prediabetes or new-onset type 2 diabetes who had gastric banding, a type of bariatric surgery for weight loss, had similar stabilization of their disease to those who took metformin alone, according to a study supported by the National Institutes of Health.

The study was published in  Diabetes Care, coinciding with a presentation during the European Association for the Study of Diabetes Annual Meeting in Berlin.

Levels Of Hormone Linked Between Diabetes And Hypertension

Physician-researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups.

This research is an important step toward finding new ways to prevent a major chronic disease. This shows how our diabetes and metabolism scientists are focused on creating a world without diabetes. The study was published in the Journal of the American Heart Association.

Medicines For Treatment In Type 2 Diabetes And On Insulin In Type 1 And Type 2 Diabetes

The World Health Organization developed these guidelines to provide guidance on selection of medicines for treatment intensification in type 2 diabetes and on use of insulin (human or analog) in type 1 and 2 diabetes. The target audience includes clinicians, policymakers, national diabetes program managers, and medicine procurement officers.

The target population is adults with type 1 or 2 diabetes in low-resource settings in low- or high-income countries. The guidelines also apply to disadvantaged populations in high-income countries.

Immune System Can Regulate Insulin

Scientists have identified a specific insulin signaling pathway that, when activated, revs up the response of T cells in the immune system to divide rapidly and secrete cytokines, chemical messenger proteins that activate the rest of the immune system.

Role Of Insulin

The role of insulin as a boost to the immune system to improve its ability to fight infection has been detailed for the first time by Toronto General Hospital Research Institute (TRI) scientists.  A fast and effective immune response protects us against disease and life-threatening infections by destroying infected cells or microbes, while a wrong or inefficient one can cause immune system disorders to develop.

The research findings are published in a paper called, "Insulin receptor-mediated stimulation boosts T cell immunity during inflammation and infection," in Cell Metabolism. 

Symptoms Of A Hormonal Imbalance

Our hormones play an enormous role in how we look, think and feel. When they’re out of balance, it can feel like we have no control over our bodies. Our body doesn’t have a voice so it communicates to us through symptoms which may be asking us to eat, drink, move, think, breathe, believe or perceive in a different way so as to better support our health. 

Incidence And Prevalence Of Type 2 Diabetes In Norway

Type 2 diabetes is one of the major chronic diseases and the patient group has increased year upon year, therefore, it is great to see the decline in the number of new cases among all the age and education groups, and among most of the immigrant groups. They hope to continue our research with annual updates that will become part of the Institute's health surveillance. It is of great interest to follow the development of type 2 diabetes over time.