Drugs called thiazolidinediones (TZDs) reverse insulin resistance in patients with type 2 diabetes by targeting the activity of a receptor protein. However, an array of side effects, including weight gain, edema, and high cholesterol, limits their use in the clinic.
Long work hours (≥60 hours / week) are associated with poor glycemic control in young Japanese men with type 2 diabetes , according to a study published in the January issue of the Journal of Diabetes Investigation .
The Henry Ford Cancer Institute announced today it has enrolled the first patient in a new clinical trial to test the effectiveness of using precise, higher dose MRI-guided radiation therapy to treat pancreatic cancer.
A new Diabetic Medicine study reveals that couples interventions may have beneficial effects for partners of individuals with type 2 diabetes. The study was a three-arm randomized telephone intervention trial comparing outcomes of couples calls (CC), individual calls (IC), and diabetes education calls (DE). While the focus of the trial was on diabetes outcomes for the patients, the authors also assessed whether partners who participated in derived benefit.
In the current issue of Family Medicine and Community Health (Volume 6,Number 4, 2018; DOI: https://doi.org/10.15212/FMCH.2018.0121, Mingliang Dai, Michael R. Peabody, Lars E. Peterson, Arch G. Mainous III of the American Board of Family Medicine, Lexington, KY 40511, USA, University of Florida, Department of Health Services Research, Management and Policy, Gainesville, FL, USA and University of Florida, Department of Community Health and Family Medicine, Gainesville, FL, USA consider how adherence to clinical guidelines is an integral part of the World Health Organization's Global Action Plan to reduce the impact of diabetes.
Large thyroid nodules in asymptomatic patients show malignancy and false-negative rates on fine needle aspiration (FNA) that are similar to those of small nodules, suggesting that nodule size alone should not be a reason for surgical resection, according to findings from a new meta-analysis.
Scientists are narrowing in on checklists of both errant genes and the environmental factors that could trigger those genes to more accurately assess type 1 diabetes risk and help children and their families avoid it.
In daily life, biological systems are usually exposed to magnetic field forces at different intensities and frequencies, either directly or indirectly. Despite negative results, the therapeutic use of the low dose magnetic field has been found in recent studies. The effect of magnetic field forces on cochlear cells is not clear in the literature.
People who are less likely to put on excess fat around their hips due to their genes are at higher risk of type 2 diabetes and heart attacks, according to a new study led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge.
Insulin-like growth factor-I regulates mitochondrial function, oxidative stress, inflammation, stellate cells, and insulin sensitivity in the liver, and it might be associated with liver fibrosis from non-alcoholic steatohepatitis (NASH).
About a quarter of all adults have metabolic syndrome; a syndrome whose most well-known symptoms are obesity, high blood pressure and poor cholesterol levels. Eating differently and exercising more is the general advice for this condition, but that is not the whole story. Ph.D. candidates Yvonne Rozendaal and Fianne Sips developed systems biology models that describe the processes of metabolic syndrome in the body in detail.
Two drugs commonly prescribed to treat Type 2 diabetes carry a high risk of cardiovascular events such as heart attack, stroke, heart failure or amputation, according to a new Northwestern Medicine study.