The researches find that Obesity does not correlate to a statistically significant difference in ICU mortality rates of patients with concomitant acute respiratory failure that requires intubation; therefore according to research present at the American Thoracic Society International Conference; held May 17-22, in Dallas, Texas; however, because of a small sample size, further studies with larger sample sizes are need for confirmation.
Acute respiratory failure
Obesity is consider to be a major risk factor in the development of many respiratory diseases; although the relationship between obesity and mortality in patients with acute respiratory failure requires further study. Therefore For this purpose; researchers conduct a retrospective study of patients in an intensive care unit who are admit for acute respiratory failure that required intubation between September 2015 and September 2017.
Body mass index (BMI) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores are collect at admission. A BMI of ≥30 classified patients as obese. Because Univariate logistic regression is use to determine the relationship between APACHE scores and mortality. Because In a cohort of 166 patients (59 women, 107 men); 71.68% (n=119) lived and 28.31% (n=47) died. A very strong relationship is find between APACHE scores and mortality (odds ratio, 1.04; 95% CI, 1.01-1.08; P =.006); with the probability of death increasing by 51.08% for every increase in APACHE score compared with a lower score previously calculated.
Probability of death
A very weak (0.563) area under the curve with threshold of an APACHE score of 21.5 was found using receiver operating characteristic analysis; and logic regression find the APACHE scores to be statistically significant (odds ratio, 2.99; 95% CI, 1.49-6.00; P =.002), indicating the probability of death is 74.95% greater for participants with calculate APACHE scores ≥21.5 compared with participants with APACHE scores ≤21.5.
Sex is not shows to be a statistically significant mortality predictor (P =.539); nor was BMI relate to mortality (P =.983). In patients with BMIs ≥30; no relationship is find between mortality and the degree of obesity (P =.848). n increased risk for stroke and systemic embolism (SE) is find among patients with newly diagnose atrial fibrillation (AF) while receiving critical care compared with those without AF; according to a study recently published in Chest.
Increased risk for stroke
This study include 30,869 adults who had survive at least 6 months after being newly diagnose with AF during critical care, as 269,751 controls with AF not diagnose in critical care and 439,868 controls with no AF. n increase risk for stroke and systemic embolism (SE) is find among patients with newly diagnose atrial fibrillation (AF) while receiving critical care compare with those without AF; according to a study recently publish in Chest.