All news from Dermatology

Drug Combination For Patients With Melanoma

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated whether the drug combinations of dabrafenib plus trametinib and of encorafenib plus binimetinib have an added benefit in comparison with the appropriate comparator therapies for patients with melanoma.

Cellulitis Risk Score May Help Guide IV Antibiotic Therapy in Children

Pediatricians from Australia have developed and validated a simple risk-assessment score to help guide about antibiotic therapy for cellulitis in children. "Cellulitis is a frequently encountered disease, but there is no evidence-based guidance to determine which children with cellulitis should be treated with intravenous antibiotics versus which can be treated with oral antibiotics," Dr. Franz Babl of the University of Melbourne.

The Rapid Genetic Linked to Skin Pigmentation

The gene that causes lighter skin pigmentation,locus in humans," according to the paper published online in the Proceedings of the National Academy of Sciences on Dec.10. Strong positive selection caused this gene to rise in frequency among some KhoeSan populations.

How Skin Cells Protect Themselves Against Stress

The skin is our largest organ, and, among other things, it provides protection against mechanical impacts. To ensure this protection, skin cells have to be connected to one another especially closely. Exactly how this mechanical stability is provided on the molecular level was unclear for a long time.

Skin Ages, Loses Fat and Immunity: More Insights

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin to plump, youthful look and producing a peptide that plays a critical role in fighting infections.