Researchers conducted a cohort study involving 82,737 women in the Nurses' Health Study II to examine the correlation between the risk for incident rosacea and caffeine intake. Caffeine intake from coffee is inversely associated with the risk for incident rosacea. The study was published online in  JAMA Dermatology.

The researchers identified 4,945 incident cases of rosacea during 1,120,051 person-years of follow-up. Increased caffeine intake was inversely associated with the risk for rosacea after adjustment for other risk factors (hazard ratio for the highest versus the lowest quintile of caffeine intake, 0.76, 95% confidence interval, 0.69 to 0.84, P <0.001 for trend).

For caffeinated coffee, there was also a significant inverse association (hazard ratio, 0.77 for those who consumed at least four servings / day versus less than one per month; 95% confidence interval, 0.69 to 0.87; P <0.001 for trend); no correlation was seen for decaffeinated coffee (hazard ratio, 0.80, 95% confidence interval, 0.56 to 1.14, P = 0.39 for  trend).

Risk Of Rosacea ???????

There was no correlation between increased caffeine intake from foods other than coffee and decreased risk for rosaceaOur findings do not support limiting caffeine intake as a preventive strategy for rosacea .

Increased caffeine intake from coffee was inversely associated with the risk of incident rosacea. Our findings do not support limiting caffeine intake as a means to prevent rosacea. Further studies are required to explain the mechanisms of action of these associations, to replicate our findings in other populations, and to explore the relationship of caffeine with different rosacea subtypes.

Further studies are required to explain the underlying mechanisms of observed associations. Several authors disclosed financial ties to the pharmaceutical industry.