White coat hypertension, a condition in which a patient's blood pressure

White coat hypertension, a condition in which a patient’s blood pressure readings are higher when take at the doctor’s office compared to other settings, was originally attributed to the anxiety patients might experience during medical appointments. However, over the years, research has suggested the elevated readings might be a sign of underlying risk for future health problems.

A new study led by researchers from Penn Medicine, publish today in the Annals of Internal Medicine, reveal that patients with untreated white coat hypertension not only have a heighten risk of heart disease, but they are twice as likely to die from heart disease than people with normal blood pressure.

White coat hypertension

Studies suggest that about one in five adults may have white coat hypertension. Our findings underscore the importance of identifying people with this condition; so said the study’s lead author Jordana B. Cohen, MD, MSCE, an assistant professor in the division of Renal-Electrolyte and Hypertension; also a senior scholar in the Center for Clinical Epidemiology and Biostatistics.

They believe individuals with isolated in-office hypertension those who are not taking blood pressure medication should be closely monitored for transition to sustained hypertension, or elevate blood pressure both at home and the doctor’s office. High blood pressure, or hypertension, is a defined as a top reading of at least 130 or a bottom one of 80. The condition affects nearly a third of American adults and, if left untreated, increases one’s risk for severe complications, including heart attack and stroke.

To diagnose and manage the condition, recent hypertension guidelines strongly recommend; so out-of-office blood pressure monitoring, such as at-home monitoring; also ambulatory blood pressure monitoring; which requires patients to wear a portable device that records blood pressure readings over a 24-hour period. However, providers have been slow to adopt this practice due, in part, to skepticism over the usefulness of screening for white coat hypertension; so given the inconsistent findings from past studies and uncertainty around its association with heart disease and death.

Death from heart disease

To identify the cardiovascular risks of white coat hypertension; so the researchers conduct a meta-analysis of 27 studies, comprising more than 60,000 patients; so that evaluated the health risks associate with the condition. They find that patients with untreated white coat hypertension had a 36% increased risk of heart disease; also 33% increased risk of death and 109% increase risk of death from heart disease.

Our findings support the pressing need for increased out-of-office blood pressure monitoring nationwide; so as it’s critical in the diagnosis and management of hypertension, Cohen said. Simultaneously, they advise individuals with untreated white coat hypertension to engage in lifestyle modifications, including smoking cessation, reduction in their alcohol intake; also making improvements to their diet and exercise regimens.

They also caution providers not to over-treat individuals with white coat hypertension; so who are already on blood pressure medication, as this could lead to dangerously low blood pressures; so outside of the office and unnecessary side effects from medication. Researchers noted that future studies are need to investigate interventions to reduce the cardiac risk of white coat hypertension.