The peripheral obstructive arterial disease develops when blood vessels narrow due to arteriosclerosis and blood flow in the legs (or sometimes the arms) becomes clogged. Intermittent claudication is when blood flow disturbances in a limb cause pain, numbness, or coldness during physical activity. In severe cases, where the tissue has gone without blood for too long and dies, the limb may have to be amputated. This research result was posted online in the Journal of American Heart Association.
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The early cardiac infiltration of monocyte-derived macrophages contributes to the development of pathological hypertrophy and fibrosis, required for the expansion of cardiac and lymphoid CD4+ and CD8+ T cells and the transition to heart failure.
Patients with acute coronary syndrome experienced a substantially lower rate of heart attack, stroke, death from cardiovascular causes and major bleeding at 12 months if the genetic information was used to inform the selection of their antiplatelet medication in a study presented at the American College of Cardiology's 67th Annual Scientific Session.
According to new research in the American Heart Association's journal Circulation, survival from cardiac arrest doubled when a bystander stepped in to apply an automated external defibrillator (AED) before emergency responders arrived.
A new study has revealed a significant link between cardiovascular disease and stroke risk in women who began menstruating before the age of 12. The study was published in the BMJ journal Heart
A new study published in the American Journal of Physiology-Heart and Circulatory Physiology revealed that irreversible dysregulation has driven by the cardiac injury, actively alters the cardiosplenic and cardiorenal networks. The new strategy or pathways that modify those networks during heart failure could be an effective approach to study either cardiac repair or pathology.
The researchers led by UNC's Jonathan Schisler have identified a possible genetic basis for coronary artery disease (CAD). They also found potential new opportunities to prevent it. They found that the CXCL5 was in elevated levels in older people without plaques. The study is published in the American Journal of Pathology.