All news from Cardiology

Urocortin 3 Gene Therapy Increases Systolic And Diastolic Function in Heart Failure

Mice with heart failure that were treated with AAV8-based gene therapy to deliver the protein urocortin 3 (UCn3) had increased blood levels of UCN3 over a 5-week period and improved heart function. The mice received a single injection of AAV8.UCn3 after cryoinjury to induce left ventricular heart failure and showed significant improvements in both systolic and diastolic heart function, as reported in an article published in  Human Gene Therapy

Heart Attacks More Common Now in Younger People, Especially Women

Heart attacks once characterized as a part of "old man's disease" -are increasingly occurring in younger people, especially women, according to new research. The study, presented Sunday at the American Heart Association's Scientific Sessions meeting in Chicago and published in the AHA journal Circulation, sought to investigate heart attacks in the young, a group frequently overlooked in cardiovascular research

Defensive ICD Programming Is Safe & Reduces Inappropriate Therapy

Sudden cardiac death is a common cause of death in patients with congenital or acquired heart disease. An implanted cardiac defibrillator (ICD) can effectively put a stop to any underlying cardiac arrhythmia. In a long-term observational study involving 1,500 patients.

Researchers have shown that the progress selected for the implanted defibrillators (ICDs) plays a major role. It was found that the most "defensive" possible procedure is safe and, at the same time, significantly reduces inappropriate therapy.

The study was published in Circulation.