The study showing the use of the nanoparticles; that could help in builiding of night vision in the humans. This explaining that photo receptors in eyes attaching by the proteins; that binds to a sugar molecule on the photoreceptor surface. As the eyes of humans and other mammals can detect light between the wavelengths of 400 and 700 nanometers; near-infrared light, on the other hand, has longer wavelengths 750 nm to 1.4 micrometers.
By injecting the photoreceptor binding UCNPs behind the retinas of the mice. To determine whether the injected mice could see and mentally process NIR light, the team conducted several physiological and behavioral tests. For example, in one test, the researchers placed the mice into a Y-shaped tank of water. One branch of the tank had a platform that the mice could climb on to escape the water. The researchers trained the mice to swim toward visible light in the shape of a triangle, which marked the escape route.
Builiding of night vision
Although the UCNPs persisted in the mice’s eyes for at least 10 weeks and did not cause any noticeable side effects, Han wants to improve the safety and sensitivity of the nanomaterials before he contemplates trying them out in humans. The UCNPs in our published paper are inorganic, and there are some drawbacks there. The biocompatibility is not completely clear, and we need to improve the brightness of the nanoparticles for human use.
the team is experimenting with UCNPs made up of two organic dyes, instead of rare-earth elements. But the study have showing that we can make organic UCNPs with much improving brightness comparing with the inorganic ones. These organic nanoparticles can emit either green or blue light. In addition to having improved properties, the organic dyes could also have fewer regulatory hurdles.
Infrared light responsive
One of the next steps for the project might be translating the technology to man’s best friend. “If we had a super dog that could see NIR light, we could project a pattern onto a lawbreaker’s’ body from a distance, and the dog could catch them without disturbing other people. Infrared light responsive photon upconversion nanoparticles possess a unique optical mechanism where long wavelength low-energy photons can be converted to high-energy emissions at the shorter wavelengths.
Superhero powers aside, the technology could also have important medical applications, such as treating diseases of the eye. But the study actually looking at how to use the NIR light to release a drug from the UNCPs specifically at the photoreceptors.