All news from Bio-Chemistry

obesity-related health issues

Fat Cell Discovery Could Help Combat Obesity-related Health Issues

Researchers have discovered differences in fat cells that could potentially identify people predisposed to metabolic diseases such as diabetes and fatty liver disease. The world-first discovery also identified ‘fast burning’ fat cells that if unlocked might help people lose weight. About 70% of Australians are overweight or obese, which has been linked to metabolic disease…

Cancer

Metabolism of Normal Cells Promotes The Metastasis

A systematic examination of the tumor and the tissue surrounding it; particularly normal cells in that tissue; called fibroblasts — has revealed a new treatment target; that could potentially prevent the rapid dissemination; and poor prognosis associated with high-grade serous carcinoma (HGSC); a tumor type that primarily originates in the fallopian tubes or ovaries and…

Biochemistry

Plant Cells Eat Their Own Membranes and Oil Droplets

Biochemists at the U.S. Department of Energy’s Brookhaven National Laboratory have discovered two ways that autophagy, or self-eating; controls the levels of oils in plant cells. The study; published in The Plant Cell; describes how this cannibalistic-sounding process actually helps plants survive. It also provides mechanistic details scientists might leverage to get plants to accumulate…

Molecules

Left or Right Handed Biomolecules

Many biomolecules come in two versions that are each other’s mirror image, like a left and a right hand. Cells generally use the left-hand version of amino acids to produce proteins; and uptake mechanisms were; thought to share this preference. University of Groningen scientists have now shown that a prokaryotic transport protein can transport both…

Biochemistry

Exposing Cancer's Metabolic Addictions

Cancerous tumors are classified primarily based on their tissue of origin. However, the sequencing of the human genome and the development of powerful and affordable DNA sequencing technologies has ushered; in a new era of precision oncology, in which patients are; treated with customized therapies designed to target the specific mutations; within their tumor. This…

New deep-learning approach predicts

New Deep-learning Approach: Protein Structure from Amino Acid

Nearly every fundamental biological process necessary for life is; carried out by proteins. They create and maintain the shapes of cells and tissues; constitute the enzymes that catalyze life-sustaining chemical reactions; act as molecular factories, transporters and motors; serve as both signal and receiver for cellular communications; and much more. Composed of long chains of…

tumor growth

Hole-forming Protein May Suppress Tumor Growth

Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism it will become. Now Jefferson researchers show a gene called gasdermin E, which is…

Low-carb breakfast improves control of blood glucose levels

Eggs for Breakfast Benefits Those with Diabetes

While some cereals may be the breakfast of champions, a UBC professor suggests people with Type 2 Diabetes (T2D) should be reaching for something else. Associate Professor Jonathan Little, who teaches in UBC Okanagan’s School of Health and Exercise Sciences, published a study this week demonstrating that a high-fat, low-carb breakfast (LCBF) can help those…

Foods

Late Dinner And No Breakfast: A Killer Combination

People who skip breakfast and eat dinner near bedtime have worse outcomes after a heart attack. That’s the finding of research published in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC). The study found that people with the two eating habits had a four to five times higher…

Blood cancer

The Leukemia Atlas: Researchers Unveil Proteins

Only about one in four people diagnosed with acute myelogenous leukemia survive five years after the initial diagnosis. To improve that survival rate; researchers at The University of Texas at San Antonio and the University of Texas MD Anderson Cancer Center; created an online atlas to identify and classify protein; signatures present at AML diagnosis.…

Staufen2 detects its target transcripts in a complex manner

RNA Transport in Neurons: Staufen2 Detects Its Target

A team of scientists from Helmholtz Zentrum München and the University of Ulm has discovered; that the neuronal transport factor Staufen2 scans and binds; to its target transcripts in a much more complex manner than previously thought. RNA is; transported within highly complex protein-RNA particles; whose structure and specificity are still; poorly understood. The team’s…

Metabolism

Patients on Statins Fail: 'Healthy' Cholesterol Level after 2 Years

Half of patients prescribed statins in primary care fail to reach ‘healthy’ cholesterol levels; after two years of treatment with these drugs; reveals research published online in the journal Heart. The findings back up those of previous studies; and highlight the need for personalised medicine to tackle high cholesterol; and lower the significantly increased risks…