All news from Bio-Chemistry

boost your brain function

Two Teaspoons Of Nuts Really Boost: Brain Function

Dementia is a cruel disease that robs people of their memory, their judgement and their identity. Unfortunately, there is no cure, and in the past few years; a number of clinical trials for new dementia drugs have failed; the latest being Biogen’s drug aducanumab. Without any effective treatments on the horizon; most people’s best hope…

Tumor growth

Protein 'Spat Out' By Cancer Cells: Promotes Tumor Growth

Prostate cancer cells change the behaviour of other cells around them; including normal cells, by ‘spitting out’ a protein from their nucleus; new research has found. The tiny pieces of protein are taken up by the other cells; provoking changes that promote tumour growth and; the researchers believe; help the cancer hide from the body’s…

Dietary intervention

Time-restricted Eating: A Dietary Intervention Against Breast Cancer

Changing when you eat rather than what you eat may prove to be a dietary intervention against breast cancer, suggests a new mouse study to be presented at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La. A growing body of evidence indicates that obesity and metabolic syndrome–a collection of risk factors that…

ketogenic weight loss diet

Females Respond Poorly To Ketogenic Weight Loss Diet

The ketogenic diet recently has been touted for weight loss and improving blood sugar control, but a new study finds that females fail to show these metabolic benefits on this high-fat, very low-carbohydrate diet. Results of the animal study will be presented Sunday at the Endocrine Society’s annual meeting in New Orleans, La. Females on…

Carbohydrate

A Strong Connection: Between Sugar And Cancer

Dr. Lewis Cantley hasn’t eaten sugar in decades. “I have a very simple rule,” he says. “I eat fruit, but I don’t eat anything that has sugar added to it. And I guarantee everybody would be better off if they ate zero sugar.” Swearing off sugar may sound like a difficult proposition in a society…

GARP Protein

GARP Protein: Target Against Colorectal Cancer

Colorectal cancer is the third leading cause of cancer-related deaths in both men and women. Despite significant advances in therapies for this particular cancer, the five-year survival rate is 12 percent, according to the American Cancer Society. Immunotherapies have emerged as a promising treatment for many cancers and are effective against melanoma, lung cancer, and…

Proteins as a biomarker

In The Eye Of A Potential Predictor: Test Of Protein Levels

Low levels of amyloid-β and tau proteins, biomarkers of Alzheimer’s disease (AD); in eye fluid were significantly associated with low cognitive scores; according to a new study published in the Journal of Alzheimer’s Disease. Led by researchers at Boston Medical Center; the study is the first to connect these known AD protein biomarkers; in the…

Enzyme to treat cancer

USP15 Enzyme For Treatment Of Cancer

Ubiquitin carboxyl-terminal hydrolase 15 is an enzyme that in humans is encoded by the USP gene. Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). So, researchers at…

Fatty acids

Free Fatty Acids: Rewire Cells To Promote Obesity-related Breast Cancer

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women’s elevated risk of developing breast cancer after menopause.”When taken up by estrogen-receptor positive breast cancer cells, these fatty acids activated pathways that increased…

Biochemistry

Membrane Protein: Between Both Lipids and Ions

The TMEM16 family of membrane proteins was hailed as representing the elusive calcium-activated chloride channels. However, the majority of the family members turned out to be scramblases, proteins that shuffle lipids between both sides of a lipid membrane, some also with non-selective ion conductance. In a new study on both mammalian and fungal proteins of…

Metabolism

SGLT-2 Inhibitors Triggers Metabolic Benefits

SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous interventions, including diet changes and metformin. Patients who take this medication see benefits that include weight loss, reduction in fatty liver disease, and a decreased risk for cardiovascular…

Protein

Selenocysteine, The Mysterious 21st Amino Acid

All the cells of an organism contain a copy of DNA in their nucleus. In order to implement the instructions it contains; this DNA must be copied into an RNA molecule; which reaches the ribosomes, which in turn read this information and synthesise proteins. The codons, animo acid triplets that form proteins; and are the…