Safety Of Transcatheter Valve Replacement

Anatomically every human being are born with an aortic valve that has three flaps tricuspid; but some are born with two of the flaps fused together, creating a bicuspid valve; by this research studying on the transcatheter valve replacement safe in those with unusual valve anatomy.

By Comparing with human being who are having a typical tricuspid aortic valve; patients with a more unusual bicuspid aortic valve had a similar rate of death; but a higher likelihood of stroke after undergoing a procedure to replace the valve by threading surgical equipment through an artery; This is the most common congenital anomaly of the heart; present in up to 1% of the general population. A bicuspid valve is more likely to leak or narrow; a condition called stenosis.

Valve replacement

This study focusing on the patients for whom open heart surgery would pose an intermediate or high risk; bolsters the case for performing transcatheter aortic valve replacement in those with a bicuspid valve who suffer from stenosis; patients with bicuspid aortic valve stenosis who are at intermediate or high risk for open heart surgery can be safely treated by balloon-expandable TAVR with an acceptable risk.

But in some severe aortic stenosis causes the heart’s aortic valve to narrow; by preventing proper flow of blood. But keeping untreated, it leads to fatigue and other symptoms and increases the risk of other heart problems. Doctors can use either TAVR or open heart surgery to restore proper functioning of the faulty valve.

Cardiovascular risk

However, TAVR to be better than or as good as conventional surgery for patients at high and intermediate cardiovascular risk; which typically includes older patients and those with multiple health problems. Research is underway to determine whether TAVR’s benefits extend to younger and often healthier people; in whom open heart surgery is less risky.

By determining TAVR’s risks and benefits in people with a bicuspid aortic valve is key to answering this question because a bicuspid valve is the most common cause of aortic stenosis in younger patients. While some previous studies have examined TAVR in those with a bicuspid valve; but they were smaller and used older types of replacement valves. Most TAVR trials have excluded patients with bicuspid aortic stenosis; leading to a paucity of data in this patient population.