Human artificial chromosomes (HACs) could be useful tools for both understanding how mammalian chromosomes function and creating synthetic biological systems, but for the last 20 years, they have been limited by an inefficient artificial centromere. In the, researchers announce that they have made progress on this key component. The centromere used to be called the…
As microtubules are protein polymers; that assemble into dynamic structures; essential for cell division, shape, motility, and transport of intracellular cargos. Proteins that regulate microtubule function and activity have been implicated in disorders ranging from Alzheimer’s disease to cancer. By learning how microtubules work, scientists hope to find new ways to treat these diseases. The plus and…
The brain’s prefrontal cortex, which gives us our ability to solve problems and plan ahead, contains billions of cells. But understanding the large diversity of cell types in this critical region, each with unique genetic and molecular properties, has been challenging. Scientists have known that much of this diversity results from epigenetics as well as…
According to the study, researchers explaining the anatomical feature of the cells pack in the epithelial tissues; as the cells in an epithelial sheet are normally connecting by the Velcro-like structures called adhesive junctions and have a near-uniform size distribution. As a result, cells related by descent tend to stick together in mosaic patches referred…
According to the study it explaining that the mitochondrial DNA revealing unexpected ancestral connections; This genetic material is finding inside mitochondria; the sub-cellular compartments or organelles where food is converted into energy. DNA from this organelle is passed down primarily from mothers to their children. During fertilisation, the father’s sperm transfers his chromosomal DNA into…
The scientists discovered that these efficient transporters belong to the voltage-dependent slow-anion channel transporter (SLAC1) clade; which also encompasses plant transporters involved in stomata closure. In contrast to other sodium or proton-dependent dicarboxylic acid transporters; SLAC1 anion channels can transport anions with virtually no expense of energy. Currently, one of the problems in industrial biotechnology…
Anatomical study finding that the sick mitochondria that pollute the cells; which cause telomere damage in the cell. Researchers showing the evidence for the long-held belief; that sick mitochondria pollute the cells they are supposed to be supplying with power. Which involving a causal experiment to kick off a mitochondrial chain reaction; that wreaks havoc…
As mitochondria, is the cell’s power stations; release quick bursts of heat by unleashing the power storing in an internal proton battery; the researchers finding. Better understanding of this process could point to new targets for treating obesity and cancer. Producing heat is part of the mitochondria’s role in the center of metabolism activity. It…
While proteins with strong mitochondrial targeting sequences can be imported into mitochondria even with a low membrane potential, proteins with weak mitochondrial targeting sequences cannot. Rolland and colleagues propose that the transcription factor ATFS-1, which has a weak mitochondrial targeting sequence, acts as a sensor, which detects and reacts to a decline in mitochondrial membrane…
Every cell consisting of many functional organs; like cilia and cell wall. As primary cilia are on virtually all cells in the body but for a long time; they were considering to be a non-functional vestigial part of the cell. To add to their mystery, they are not present all the time. They project from…
Study in a cell showing that runaway mitochondria cause telomere damage in cells; the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they are supposing to be supplying with power. This involving a causal experiment to kick off a mitochondrial chain reaction that wreaks havoc on the cell, all the…
According to the research study, researchers identifying the fundamental properties of the cells; that affect how tissue structures form. These finding that changing the mechanical properties of individual cells disrupts their ability to remain stable; and profoundly affecting their health and the health of the tissue that comprises them. The LINC complex a group of…