Researchers from the University of Surrey and Royal Surrey County Hospital are undertaking exciting new research to help improve survival rates of men with metastatic prostate cancer.

The researchers will investigate the impact of high-intensity aerobic and resistance training combined with psychosocial support on men with prostate cancer. During this worldwide study, the team will provide an exercise program for 866 men with prostate cancer over a 3-year period at sites across Australia, North America, and Europe.

The research team at Surrey is led by Professor Hardev Pandha (Medical Oncology), Professor Sara Faithfull (Cancer Nursing Practice) and Dr. Ralph Manders (Exercise Physiology).

"The benefit of exercise to both our physical and mental well-being is undeniable. What we are hoping to uncover is whether the same benefits are experienced when a person is living with cancer, and whether it extends their survival from cancer. If it does this could be revolutionary in the future of treating and supporting people with prostate cancer," said Dr. Ralph Manders.

During the study, participants will be split into two groups, those who will embark on an exercise training program with supplementary behavioral and psychosocial support (intervention arm) and those who will receive psychosocial support only (control arm) but can follow their usual exercise and lifestyle routine.

Those in the intervention arm will complete exercise training three times a week, which will be initially supervised prior to becoming more self-managed, while receiving text messages to provide behavioral support and tailored newsletters to provide psychosocial support. Participants in the control arm will receive psychosocial support via the newsletters.

All participants will remain on the study for 24 cycles, each lasting 28 days. Throughout the study, researchers will be measuring survival time, disease progression, symptomatic skeletal-related events, pain medications, symptoms, metabolic and inflammatory markers to assess the impact of exercise on men with prostate cancer.

Sam Gledhill, Movember Foundation said, "Conventional treatments and therapies remain the primary means of attack against prostate cancer. However, incremental improvements that can be achieved by other means all amount to valuable extra time and quality of life for men diagnosed with the disease."