All news from Anaesthesiology

Time Not Only Factor In Emergency Care

Researchers have been taking a closer look at what happens in the brain during and after a stroke, particularly at patterns of blood circulation. We need to rethink a basic rule that has guided stroke care for the past 25 years, declares the brain specialist who first proposed it. The study was published in the Journal of Stroke & Cerebrovascular Diseases. 

A stroke occurs when the blood supply to a part of the brain stops and cells begin to die due to lack of oxygen and nutrients. There are two main types of stroke: ischemic and hemorrhagic. Ischemic strokes, which result from clots or blood vessel constrictions, are by far the most common. Hemorrhagic strokes occur when vessels burst.

Most Powerful Electron Microscope Can Capture Objects Of Picometres In Size

Two Nobel laureates launched what has been dubbed “Australia’s most advanced electron microscope” at the University of Sydney’s Nanoscience Hub this week. The 4.5 m tall Thermo Fisher Themis-Z transmission electron microscope is so powerful it can capture objects that are mere picometres in size or one trillionth of a meter.

It can see down to levels of about 0.06 nanometers, which is about half the size of a hydrogen atom,” said New South Wales Chief Scientist and Engineer Professor Hugh Durrant-Whyte at the launch event.

Regional Anesthetic Technique Increased The Rate Of Surgery

Regional anesthetic technique increased the success of surgery even one year after the procedure, according to a study comparing regional anesthetic and local anesthetic technique at the time of surgery. Researchers investigators examined patients who received a surgically created fistula to enable dialysis for end-stage kidney disease. The study was published in The Lancet.

Molecules May Increase Cardiovascular Risk From Early Life Stress

The release of "danger" molecules in response to significant periods of mental stress early in life may leave young people at lifelong risk of cardiovascular disease. They know mental stress is bad for the cardiovascular system.

They want to know more about how it's bad. They think one answer is DAMPs, or damage (AKA "danger") associated molecular patterns. Stressed and dying cells regularly empty their contents or DAMPs.

Align Body's Internal Clock: Researchers Say

Researchers have linked circadian health to the risk of diabetes, cardiovascular disease, and neurodegeneration. It’s also known that the timing of meals and medicines can influence how they are metabolized.

Body’s internal clock, the circadian rhythm regulates an enormous variety of processes: when you sleep and wake, when you’re hungry, when you’re most productive. Given its palpable effect on so much of our lives, it’s not surprising that it has an enormous impact on our health as well.

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

Researchers have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition.

By identifying caspase-2's critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH and possibly even reverse early symptoms. The findings are published in the September 13 online issue of Cell.