Scientists at Tokyo Institute of Technology designed a novel data analysis technique, moving subtrajectory analysis which explains the dynamics and kinetics of significant molecules in the immune response to an infection and these explanations clarified the TCR microcluster; a crucial assembly for a T cell to initiate its attack on a pathogen and sustain the immune signal.
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Researchers at Universitaet Tübingen have developed a new method to target specific cell types in mice and monitor their behaviour using Positron Emission Tomography (PET). PET-based cell tracking would aid to observe complex life processes in the body without exposing test animals to invasive methods and thus reduce the use of test animals. The results were published in the journal Nature Communications.
The visual hallucinations in patients with Parkinson's disease might be contributed by the disconnections of the brain areas involved in attention and visual processing, published in the journal Radiology.
Tuberculosis remained as one of the most widespread life-threatening infectious diseases. The researchers have developed a structural analogue of mycolic acid, the essential membrane building block. Since antibiotic resistance makes treatment increasingly difficult. Moreover, the effectiveness of many drugs was limited due to bacteria's relatively impermeable mycomembrane. The findings of the study has appeared in the journal Angewandte Chemie
Forensic entomology is the use of the insects, and their arthropod relatives that inhabit decomposing remains to aid legal investigations. These insects act as indicators of post-mortem displacement, the study quoted.
Researchers have developed a genetic test, PancreaSeq®, which proved to be highly sensitive to determine pancreatic cysts that are most associated with one of the aggressive types of pancreatic cancer. The study was reported in Gut, the journal of the British Society of Gastroenterology.
A new study, in the journal Radiology, recognized that structural deformity in the brains of people with genetic autism. The deformities marked on brain images were related to cognitive and developmental impairments in the study group. This suggests the future significance of imaging in identifying autism and recommends intervention to them.
According to the study presented at the 15th Urological Association of Asia Congress (UAA 2017) held in Hong Kong, replacement of cancer tissue with blood samples (liquid biopsy) to recognise circulating tumour cells (CTCs), circulating tumour DNA (ctDNA) and microRNA (miRNA) proved to be beneficial in detecting progression and predicting prognosis of patients with bladder cancer.
A study of emergency department (ED) procedural sedation available in JAMA Pediatrics, has found ketamine alone to have less serious adverse events (SAEs) and significant interventions in children when compared with propofol alone or ketamine combined with propofol or fentanyl.
The doctors should minimize or avoid prescribing over antibiotics. As a new research conducted at the University Of Virginia School Of Medicine found that the misuse of antibiotics may have major effects on the body’s immune system. The researchers showed that overuse of antibiotics weakens the body’s immunity to the disease.
A new study revealed a new healing capacity of the heart which was not identified earlier. Researchers reversed severe heart failure by inhibiting the activity of Hippo (a signaling pathway that can prevent the regeneration of heart muscle) in a mouse model. The study published in the journal Nature.
Hepatitis A virus causes Hepatitis A infection, which is an acute infection of the liver. Where it leaves for short-term but causes severe infection to the liver. Symptoms of this infection include fever, weakness, nausea, aches, aches and jaundice.