All news from Anaesthesiology

New genetic syndrome increased the risk of early tumour formation and chemotherapy toxicity

A new study led by Jordi Surrallés, lead investigator at the Centre for Biomedical Network Research on Rare Diseases (CIBERER) recognised that a new genetic syndrome caused by biallelic mutations increased the risk of early cancer formation and caused rejection to chemotherapy treatments. Hence, scientists advised modifying the clinical treatment for people with these mutations.

Mutations produced in both copies of the FANCM gene known as biallelic mutations. In Contrast, scientists found that the gene didn’t cause Fanconi anaemia. The research was published in Genetics in Medicine.       

NASA's twin study explores the ground truth of metabolites

According to the metabolomics data, the body is percolating some expressive information about our everyday life.  Tejaswini Mishra, Ph.D. Postdoctoral fellow from Stanford University School of Medicine, said,  "Metabolomics measures small molecules called metabolites that reflect the physiology of the body, and can reveal specific details about you. Researchers can see specific metabolites — such as caffeine — in your blood, and form hypotheses about your diet, lifestyle or environment.

Mental Health Issues Caused by Childhood Bullying Decline Over Time

According to the study published in Psychiatry, the detrimental effects that showed potential for resilience in children exposed to bullying decreased over time. In previous studies, it was shown that bullied children are more likely to suffer mental health issues. However, a little evidence of a causal link was given, as pre-existing vulnerabilities that can make youngsters both more likely to be bullied and experience worse mental health outcomes.

Life-limiting disease triggered by a harmful protein on acid, study finds

Researchers revealed the unidentified effects of acidity on a small protein called serum amyloid A (SAA) by using current biochemical and structural biology techniques. The results, available in the journal Proceedings of the National Academy of Sciences, could support to plan new treatments for the deadly human disorder called secondary systemic amyloidosis (AA). In amyloidosis, abnormal proteins build up in tissues and organs.

Asthma-Like Coughing and Wheezing: Children without Allergies May Also Be the Victims

In a new research from Cleveland Clinic, a protein was found to be responsible for the allergies characterized by asthma-like coughing and wheezing observed in children. A protein, transient receptor potential vanilloid 1(TRPV1) was found to be involved in airway disease through mucus production, cough reflex stimulation and airway narrowing. The asthma-like symptoms in children were observed even in the absence of allergies. The study is published in the Journal of Allergy and Clinical Immunology.

Nanochip could heal organ with single touch

A tiny nanotechnology device could modify the cell functions and revive the failing organs with a single touch. The technique is known as Tissue Nano transfection (TNT) which delivers a new genetic code into the skin cells. These genetically modified skin cells were then transformed to get the diseased cells. The study is available in the journal Nature Nanotechnology.