All news from Anaesthesiology

Dengue: study related to indoor spraying to help its prevention

The prevention of dengue, the most prevalent mosquito-borne virus in the world, relies heavily on controlling mosquito populations, as the currently available dengue vaccine is only partially effective. Indoor spraying — which involves spraying of insecticides inside houses — has the potential to be a key part of those prevention efforts, researchers report.The study is published in PLOS Neglected Tropical Diseases.

Returning of Skin Cancer Predicted by Blood Test

In a new study published in the Annals of Oncology, the researchers have discovered that testing skin cancer patients' blood for tumour DNA could predict the likelihoods of aggressive cancer returning.The study findings could pave the way to identifying patients who are most at risk of their disease returning, and who might benefit from new immunotherapy treatments.

Research, More complex biological systems evolve more freely

Evolution acts on changes in the phenotype, which occur when mutations change the underlying genotype. But the changes to the phenotype that can be produced by mutations is not without bounds. Researchers found that in a gene regulatory system in the bacterium Escherichia coli, the more components that are mutated, the more freely the system can evolve.

PET: Therapy Response Assessment in Glioblastoma

Tumor biology measured by advanced MRI and positron emission tomography (PET) imaging, which may precede anatomical changes of the tumor volume, is promising. Imaging biomarkers capable of predicting response at an early time point after treatment initiation are the premise of personalized treatment enabling change or discontinuation of therapy to prevent ineffective treatment or adverse events of treatment.

An overview of applicable PET tracers for the therapy response assessment in GB and the determination of tumor recurrence versus treatment-related effects is given.

Doctors Struggle to Cope with Anxiety in Critically Ill Patients

A new study led by UCL researchers have shown that, although it is a common problem, doctors struggle to manage anxiety in their critically ill patients. The findings emphasize the key issues in terms of how anxiety is assessed and managed in critically ill patients, including; infrequent use of screening tools, poor access to mental health services, and wide variations in prescribing practice.

Acute postanesthesia pain care unit in postoperative pain management

Studies on postoperative pain management in the PACU were reviewed for the advances in assessments and treatments. More objective assessments of pain being independent of patients’ participation may be potentially appropriate in the PACU, including photoplethysmography-derived parameters, analgesia nociception index, skin conductance, and pupillometry, although further studies are needed to confirm their utilities. Multimodal analgesia with different analgesics and techniques has been widely used.

Injury from contact sport has ill effect on memory

Neuroscientists studying sports-related head injuries have found that it takes less than a full concussion to cause memory loss, possibly because even mild trauma can interrupt the production of new neurons in a region of the brain responsible for memory.

The findings were presented at the Society for Neuroscience's annual conference, Neuroscience 2017.