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Gene Therapy Via Skin Protects From Lethal Cocaine Doses

There are no approved medications to treat either cocaine addiction or overdose. Frequent users tend to become less and less sensitive to the drug, leading to stronger or more frequent doses. The typical result is an addiction. Exposure to the drug, or to drug-associated cues, even after long periods of abstention, often leads to relapse

Near-atomic Cryo-EM Imaging Of A Small Protein Displayed On A Designed Scaffolding System

Biochemists have achieved a major goal in biology: seeing at near atomic detail the smallest protein ever visualized by the technique whose development won the 2017 Nobel Prize in chemistry. Until now, this method has not worked with the small proteins inside cells.

UCLA biochemists have achieved a first in biology: viewing at the near-atomic detail the smallest protein ever seen by the technique whose development won its creators the 2017 Nobel Prize in chemistry.

That technique, called cryo-electron microscopy, enables scientists to see large biomolecules, such as viruses, in extraordinary detail. The research is published in the journal Proceedings of the National Academy of Sciences.