All news from Anaesthesiology

A new method for treating patients with a rare dermatologic disease

Researchers found a new treatment for a rare and often incurable condition called dermatomyositis(DM), this has reduced the severity of disease in patients. They conducted a test on 22 patients; these patients were treated with a drug called anabasum or placebo. After trailing on them, 11 patients showing with a drug improvement in the trial period. They showed less skin disease and the quality of life was better. These findings are done at the American College of Rheumatology.

High-intensity exercises could Delay Parkinson's Disease Progression

The scientist from University of Colorado Anschutz Medical Campus and Northwestern Medicine led the first study to evaluate the effects of high-intensity exercise on patients with Parkinson's disease. They found that high-intensity exercise three times a week is safe for individuals with early-stage Parkinson's disease and decreases worsening of motor symptoms. The study was published in the December issue of JAMA Neurology,

Outpatient Total Knee Replacement Surgery Associated With Higher Rates of Complications

Armin Arshi, MD, of the David Geffen School of Medicine at UCLA and colleagues conducted the studies.According to the new research, when compared to conventional inpatient surgery, patients undergoing outpatient total knee arthroplasty (TKA) experience higher rates of certain complications, including infections, repeat surgery, and blood clots.The study reports were published in The Journal of Bone & Joint Surgery

Cardiovascular risk in adulthood associated with abuse and adversity faced in childhood

Children and teens who experience abuse, bullying, neglect or witness violence and other forms of adversity are more likely to develop heart and blood vessel diseases as adults. Unhealthy responses to stress (such as overeating), mental health problems and disruptions in basic biologic processes may underlie the increased risk. The findings are according to a new scientific statement by the American Heart Association published in the Association's journal Circulation.

More Promising Combination Therapy for Ovarian Cancers

Researchers at The Wistar Institute have found that combining PARP inhibitors, poly ADP ribose polymerase enzyme inhibitor recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations. This study was published online in Cell Reports.

Mechanism behind the Neuron Development Was Revealed

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have now uncovered new insights into the regulatory network behind that termination. The study, led by TSRI Associate Professor Brock Grill, PhD, was recently published  in the journal Development. Using the nematode worm C. elegans as a model, Grill and his colleagues found for the first time that growth cone collapse prior to axon termination is protracted as the growth cone transitions from a dynamic to a static state.