Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, Ph.D., collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage. Their findings appear today in Nature Communications
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Scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) have identified new means of fighting drug-tolerant bacteria, a growing global threat as menacing as drug-resistant microbes. Little is known about the mechanisms leading to tolerance, a strategy that makes bacteria "indifferent" to antibiotics and almost "un-killable," which results in chronic infections extremely difficult to treat and cure.
A new study from the University of Iowa finds that type 2 diabetes remains overwhelmingly the most common type of diabetes diagnosed in American adults who have the disease. The study found that 8.5% of American adults have been diagnosed with type 2 diabetes and 5% with type 1 diabetes.
Among those who are diagnosed with diabetes, 91.2% have type 2 diabetes and 5.6% have type 1 diabetes. The study was published in the British Medical Journal.
As one of the most common malignant tumors, gastric cancer (GC) occupies the second leading cause of cancer-related deaths worldwide with an increasing trend.
The use of a brief sleep intervention provided in the first months of life and designed to improve sleep habits from birth is associated with a reduced risk of obesity up to age 5, according to new research
A clinical trial to find a better treatment for severe or chronic cases of post kala-azar dermal leishmaniasis (PKDL) in Africa has begun in Dooka, Sudan. The objective of this clinical trial, which is being conducted by the Drugs for Neglected Diseases initiative (DNDi), is to shorten the length of hospitalization for PKDL and deliver a treatment that is safer to use and easier to administer.
New findings of hematopoietic stem cells which give rise to all blood cells could lead to improvements in bone marrow transplantation. The liver is the surprising source of a growth factor that keeps bone marrow stem cells healthy. In bone marrow transplantation often used to treat blood cancer healthy bone marrow cells are transferred to a patient to replace diseased cells.
The study, published in the latest issue of Science, uncovered the source of a key growth factor that, in mice, keeps blood-forming hematopoietic stem cells (HSCs) in a healthy state inside bone marrow. Without the growth factor, HSCs cannot maintain themselves or create new blood cells
Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce their pain as effectively as any powerful drug on the market, according to new research
Epidemiological studies have established a strong correlation between inhaling ultrafine particles from incomplete combustion and respiratory and cardiovascular diseases. Still, relatively little is known about the mechanisms behind how air particulates affect human health. New work with carbon nanodots seeks to provide the first model of how ultrafine carbon-based particles interact with the lung tissues.
New findings at the molecular level of polymerases can be used for genome sequencing and other areas of molecular biology-based diagnostics. Complex biological systems can be described as a network of chemical processes that take place in molecules.
The scientists of the "Chemie" research initiative at the University of Konstanz are working together in an equally active network with dynamic interconnections both subject-specific and interdisciplinary. The research results were published on 17 September 2018 in the Proceedings of the National Academy of Sciences (PNAS).