According to a new study published in the issue of Cell Reports, helper T cells move toward inflamed tissue using membrane protrusions that stabilize them and provide traction on the vasculature. Using high-resolution microscopy and global molecular analysis, the team shows that immature T cells lack these protrusions but that maturing T-cells switch on a gene expression program to create material to construct them.
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New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells). Conducted largely in genetic models of obese mice, it shows obesity causes durable and harmful changes to the hematopoietic stem cell compartment – the blood-making factory in our bodies.Researchers at the Cincinnati Children's Cancer and Blood Diseases Institute conducted the study.
In an effort to provide patients the opportunity to share practical health consumer perspectives, the Clinical Journal of the American Society of Nephrology (CJASN) is including Patient Voice editorials that will accompany certain journal articles. In the first editorial, Paul T. Conway, a past recipient of the ASN President's medal, highlights 2 CJASN articles that focus on patient comprehension of how treatments align with their individual interests.
Getting the ‘right resource to the right patient at the right place at the right time’ is something that we as physicians should achieve for our patients, and EMS can really help with that. Paramedics are healthcare providers, not just a transport resource.
The university that employed a controversial herpes vaccine researcher has told the federal government it learned last summer of the possibility of his illegal experimentation on human subjects. But Southern Illinois University did not publicly disclose the tip or its findings about researcher William Halford's misconduct for months, according to a memo obtained by Kaiser Health News.
Relational security is an important component of care and risk assessment in mental health services, but the utility of available measures remains under-researched. The present study analyzed the psychometric properties of two relational security tools; the See Think Act (STA) scale and the Relational Security Explorer (RSE).
Researchers observed that Patients with type 2 diabetes are least likely to adhere to the most commonly prescribed medication for their disease, potentially because of its adverse-event profile. This was published in Diabetes, Obesity and Metabolism .
Ten years after the Hepatitis B vaccine was introduced in the Universal Immunisation Programme (UIP), the Union health ministry plans to assess the impact of the immunization on the population.
The randomized controlled trial of more than 2,000 people in Lambeth and Southwark was led by the London School of Hygiene & Tropical Medicine and King's College London, in partnership with SH:24, a digital sexual health service. The study found testing uptake was nearly doubled in a group that was invited to use internet-accessed STI testing (e-STI testing) compared to a group which was invited to use existing services at health clinics (50% e-STI testing group compared to 26.6% control group). Participants were free to use any other service or intervention during the study period.
Scientists have demonstrated that skiing and running can delay aging. This is essential because of the direct positive impact on the body due to proper exercise and physical fitness.
The Cardiovascular Surgery Group at Osaka University successfully implanted a left ventricular assist device with an internal power cable tunnelled through the neck to the head in a patient who was ineligible for a cardiac transplantation, destination therapy (DT) trial.