New drugs translate to the advancement of health care in the United States, and each year the CDER approves a wide range of new drugs and biological products. In 2015 and 2016, the FDA approved 45 and 29 new therapies, respectively. This year, the FDA is on pace to approve about 38 new medications. Additions to the drug market this year cover a variety of diseases and ailments, providing prescribers with more options and the ability to optimize drug therapy.
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A new approach, published in the journal Small Methods, to reducing bulging tummy fats has shown promise in laboratory trials. The discovery could help to address the worldwide obesity problem without resorting to surgical operations or oral medication which could require large dosages and could have serious side effects.
A recently demonstrated randomized trial compared APRV versus the current standard of care, low-tidal-volume ventilation (LTV). Although many consider APRV to be a "rescue mode" for refractory hypoxemia, others argue that it minimizes ventilator-induced lung injury and maintain that APRV should be the primary mode of ventilation for patients with ARDS. This study was published in The American Journal of Respiratory and Critical Care Medicine.
A Swedish study suggests that light massage could reduce pain, anxiety and the need for opioid medication in terminally ill patients. “All end-of-life patients experience existential pain or existential suffering,” Linda Bjorkhem-Bergman reported. “This pain is difficult to treat pharmacologically and complementary methods, such as massage, provide an alternative.”
The mild infections may make a large contribution to antibiotic use, and could have a big impact on resistance evolution. A new study published in the journal PLOS Biology suggests that development of alternative therapies for mild infections could help slow the development and spread of antibiotic resistance, thereby preserving the drugs' effectiveness for use in severe infections.
The drug, called pentyl pantothenamide , is able to stop the growth of E.coli but not completely kill the bacterium, so it was never taken into clinical use.The study findings were published in the journal Biochemistry , open up the possibility of designing new drugs that use the same means to attack E. coli, but in a more effective way.
Of every 100 Americans who drink (140 million), about 12 (16 million) are considered in need of treatment for an alcohol use disorder, and eight will become chemically dependent on alcohol. Of that eight, one will become addicted very early, even after the first drunken episode. The problem is, we do not yet have a way to predict who that one person will be.
According to a new research, adding a paracervical block to general anesthesia for endometrial ablation reduces pain and the need for postoperative narcotics.
Dr. Jordan S. Klebanoff of Christiana Care Health System in Newark reported, "Our study showed that women who received a paracervical block at the completion of their endometrial ablation had less pain at one hour postoperatively. In addition, less immediate postoperative narcotic medication was required."
According to a systematic review and meta-analysis , Surgeons and medical interventionalists are at high risk for work-related musculoskeletal disorders , with rates comparable to construction workers. The study findings were published in the JAMA Surgery .
In a new study presented at the meeting of the American Society of Haematology (ASH) conference, the researchers suggested that forging AI (Artificial intelligence) with genomics will push precision medicine forward in blood cancer and lead to new insights and discoveries.
Education and research about concussions in youth have focused on team sports, but a study from New Mexico suggests that adolescents may suffer more knock-out head blows in PE classes than in organized athletics. The findings are reported online in the American Journal of Public Health.