All news from Anaesthesiology

Nanoparticles Destroy Wide Group Of Viruses

An international group of researchers have designed new anti-viral nanoparticles that bind to a range of viruses, including herpes simplex virus, human papillomavirus, respiratory syncytial virus and Dengue and Lentiviruses. Unlike other broad-spectrum antivirals, which simply prevent viruses from infecting cells, the new nanoparticles destroy viruses. This study has been published in the journal Nature Materials.

Childrens Injured From Window Blinds Were Send To Emergency Department Every Day

A study demonstrates that continued deaths from strangulation on window blind cords demonstrate urgent need for stronger safety standards. Almost 17,000 children under six years of age were treated in hospital emergency departments in the US for window blind-related injuries from 1990 through 2015, averaging almost two per day. While the majority of children were treated and released, there was about one child death each month — most from strangulation when a child became entangled by the neck in a window blind cord.

Toxic Ion Flow linked to Alzheimer's Disease Blocked with a Experimental Drug

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease. The drug works by stopping toxic ion flow in the brain that is known to trigger nerve cell death. Scientists envision that this drug could be used to treat Alzheimer's and other neurodegenerative diseases such as Parkinson's and ALS. Researchers published their findings in EMBO Molecular Medicine.

High rate of mortality from sepsis in ICUs

Brazil has an extremely high rate of mortality from sepsis in intensive care units (ICUs), surpassing even mortality due to stroke and heart attack in ICUs. According to a survey conducted by researchers at the Federal University of Sao Paulo (UNIFESP) and the Latin American Sepsis Institute (LASI), over 230,000 adults die from sepsis in ICUs every year and about 55.7% of sepsis cases in ICUs end in death.

In A Developing Heart, Blood Flow Monitors The Maturation Of Heart Valves

Researchers from the Perelman School of Medicine at the University of Pennsylvania have found that the force, or shear, of blood flow against the cells lining the early heart valve sends signals for heart "cushion" cells to become fully formed valves. Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. This study has been published in Developmental Cell.

Eotaxin-1 (CCL11) Is Detectable in Transfusion Blood Products

High blood levels of the chemokine eotaxin-1 (CCL11) have recently been associated with aging and dementia, as well as impaired memory and learning in humans. Importantly, eotaxin-1 was shown to pass the blood-brain-barrier (BBB) and has been identified as crucial mediator of decreased neurogenesis and cognitive impairment in young mice after being surgically connected to the vessel system of old animals in a parabiosis model.

Selenium protects specialized neurons from cell death

About 200 years ago, the Swedish scientist Jöns Jacob Berzelius discovered the trace element selenium, which he named after the goddess of the moon, Selene. Besides its industrial applications (chemical industry, production of semiconductors and toners), selenium is an essential trace element and indispensable for humans, many animals, and some bacteria. A team led by Dr. Marcus Conrad, research group leader at the Institute of Developmental Genetics (IDG), showed for the first time why selenium is a limiting factor for mammals.

Treatment For Pharmacogenetics And Psoriasis Are Possible

According to researchers, Autoimmune disease, characterized by the host's immune response against self-antigens, manifests in more than 100 different types and affects more than 10% of the world's population, causing significant morbidity and high financial burden. Psoriasis (PS), is amongst the most common autoimmune diseases affecting approximately 2% of people globally, while it can also be a great model disease.