All news from Anaesthesiology

New Gene Therapy for Rare Form of Vision Loss Approved By FDA

Voretigene neparvovec-rzyl ( Luxturna , Spark Therapeutics) is targeted for adults and children with confirmed biallelic  RPE65  mutation-associated retinal dystrophy. The treatment, which is delivered surgically via subretinal injection , is the first gene therapy approved in the United States that targets a disease caused by mutations in a specific gene.

Cardiovascular Risk is an Early Sign in ADPKD

The aim of the study was to identify early and noninvasive markers of cardiovascular risk in young ADPKD patients, in the early stages of the disease.Cardiovascular disease is the most frequent cause of morbidity and mortality in autosomal dominant polycystic kidney disease ( ADPKD ) patients, often before the onset of  renal failure , and the pathogenetic mechanism is not yet well elucidated.

Genetic diversity in Malaria parasite in the Americas

Researchers discover that populations of Plasmodium vivax on the continent are as genetically diverse as in Southeast Asia, where malaria transmission is more frequent. Vivax's greater genetic diversity in the Americas in comparison with Falciparum species might be explained by a wider range of migratory routes.