The researchers explored that the folic acid supplementation and folate status in pregnancy are associated with reduced risk of autistic traits owing to in utero AED exposure. The study findings were published in the JAMA Neurology
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Marketing authorization of darvadstrocel for treatment of refractory complex perianal fistulas in patients with Crohn's disease has been recommended by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA).
New dipstick technology that enables pathogen detection and the rapid diagnosis of human, animal and plant disease in even the most remote locations has been developed by University of Queensland scientists.
Paul Brown from the University of Calgary led a study to find out just how much exercise is needed during hemodialysis, a treatment that uses a machine to filter the body's blood and remove toxins when the kidneys are not functioning. The study findings were published in the Applied Physiology, Nutrition, and Metabolism
According to a new study, researchers aimed to compare the accuracy, measured as priority level, between two Swedish dispatch protocols, the three-graded priority protocol Medical Index and a newly developed prototype, the four-graded priority protocol, RETTS-A. Emergency medical dispatching should be as accurate as possible to ensure patient safety and optimize the use of ambulance resources.
Lyme disease is caused by a bacterium known as Borrellia burgdorferi and is transmitted by the bite of Ixodid tick. It is one of the most reported vector-borne diseases worldwide. Centers for Disease Control and Prevention (CDC, USA) estimated that approximately 300,000 cases of Lyme disease occur each year.
Studies in mice and in tissue cultures suggest that giving vitamin C with tuberculosis drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen. The research is published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.
Scientists at the National Eye Institute (NEI) report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE). The discovery has advanced efforts to make stem cell-derived RPE for transplantation into patients with geographic atrophy, otherwise known as dry age-related macular degeneration (AMD). The study findings were published in the Cell Reports.
Researchers declined that a potential strategy targets metabolic pathways that are active only during intestinal inflammation prevented or reduced inflammation in a mouse model of colitis while exerting no obvious effect in control animals with healthy, balanced bacterial populations. They have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis.
The microfluidic device, which can be used in clinics, is dubbed SPARTAN, short for Simple Periodic ARray for Trapping And IsolatioN. It uses a field of three-dimensional posts that create an obstacle course for the swimming sperm cells. The strongest and healthiest sperm get through this array the fastest and then are collected at the outlet to be used in the in vitro fertilization (IVF) process.
In the study, when sucrose compared to octasulfate to placebo dressing in 240 patients with neuroischemic diabetic foot ulcers, wound healing was knowingly improved among patients given the active dressing. Currently there are no proven treatments for neuroischemic ulcers, defined as those arising in the presence of both peripheral neuropathy and peripheral arterial disease, with the latter condition significantly worsening prognosis. This study was published in Lancet Diabetes & Endocrinology.
The study to make substantial improvements in the treatment of Alzheimer's disease through the use of a drug originally created to treat type 2 diabetes. The study was published in the Brain Research.