All news from Anaesthesiology

PlaqueTec Liquid Biopsy System Feasible to detect Biomarkers for CAD

New open?access article published in the 1 issue of the Journal of the American College of Cardiology [JACC] has revealed the feasibility and potential of the PlaqueTec Liquid Biopsy System™ (LBS) to detect biomarkers for coronary artery disease (CAD). The system reported results from the first?in?human studies of the LBS in detecting biomolecular gradients in diseased coronary arteries of symptomatic patients undergoing percutaneous coronary intervention (PCI) procedures.  

Biorelevant nanomaterials synthesis

Artificial polyelectrolytes can mimic the interactions of biological macromolecules such as nucleic acids, proteins, and polysaccharide-protein conjugates. Such synthetic polyionic complexes are expected to serve as novel platforms to stabilize and deliver drugs, proteins, or nucleic acids. In the journal Angewandte Chemie, Chinese investigators have introduced a versatile, commercially applicable preparation strategy of such nanomaterials with tunable morphology. The preparation of libraries of these low-dimensional bio-relevant nanostructures can be envisaged.

An early supportive care might be triggered by common cold

The study found that other signs of respiratory distress, such as low arterial blood oxygen or rapid shallow breathing, were no more common in severely premature children (less than 32 weeks of gestational age) than in kids born preterm or full-term. The findings have implications for administering supportive care sooner or more intensively for severely premature children than for other infants.

Diversity of Monocytes

New research published in the journal Immunity, has revealed that the monocyte-derived dendritic cells are not identical descendants, but rather a very diverse mixture. The finding is important for the further development of tailor-made immunotherapies for combating tumour cells.

Cancer mortality: Decades-long drop

The cancer death rate dropped 1.7% from 2014 to 2015, continuing a drop that began in 1991 and has reached 26%, resulting in nearly 2.4 million fewer cancer deaths during that time. The data is reported in Cancer Statistics 2018, the American Cancer Society's comprehensive annual report on cancer incidence, mortality, and survival. It is published in CA: A Cancer Journal for Clinicians and is accompanied by its consumer version: Cancer Facts and Figures 2018.