All news from Anaesthesiology

Biosensor Response From Target Molecules With Inhomogeneous Charge Localization

Clinicians most often monitor antibodies because these small proteins attach to antigens or foreign substances, we face every day. Most biomolecules, however, have complicated charge characteristics, and the sensor response from conventional carbon nanotube systems can be erratic.

A team recently revealed how these systems work and proposed changes to dramatically improve biomolecule detection. The study was published in the Journal of Applied Physics.

More Women Than Men Veterans With Chronic Pain Use Therapies Like Yoga and Acupuncture

A recent major shift in practice by the Veterans Health Administration (VA) now means that complementary and integrative health (CIH) therapies such as meditation, yoga, and acupuncture are increasingly being offered to VA patients as non-drug approaches for pain management and related conditions, says Elizabeth Evans, an epidemiology researcher in the School of Public Health and Health Sciences at the University of Massachusetts Amherst

Taking Care of Older Adults Living With HIV

The advent of highly active antiretroviral therapy in the mid-1990s has enabled people living with HIV to achieve a normal or close-to-normal life expectancy, the effect of which is now being realized. In 2014, approximately 45% of people living with HIV in the United States were aged ≥50 years, 27% were aged ≥55 years, and 6% were aged ≥65 years.

Although new HIV diagnoses among people aged ≥50 years decreased by 10% from 2010 to 2014, this age group still accounted for 17% of new HIV diagnoses in 2015.  Despite such data, HIV/AIDS in the United States is still thought of by many as a disease of young adults, and this is where the majority of screening and prevention efforts have continued.

Subsequently, many older adults are not being diagnosed until later stages. In 2014, 40% of patients aged ≥55 years had advanced to AIDS by the time they received their HIV diagnosis. Ageism perpetuates the invisibility of older adults, which renders current medical and social service systems unprepared to respond to the needs of people aging with HIV infection.

Major Facilities In ICU Is Sedation

Sedation is one of the main facilities in the intensive care unit (ICU). However, it is well known that no sedation, or minimizing it, results in better outcomes, such as decreased length of hospital stay, shorter duration of mechanical ventilation, reduced health care costs and a reduced need for additional examinations to determine brain function.

It is also related to early mobilization of the patient, but it is unclear if it decreases delirium. Most of the review studies supporting this evidence are based on populations with non-acute brain injury. Traditionally, these patients were kept under sedation in the early phase to prevent the secondary insult.

Stem Cells Can Make New Cartilage And Repair Damaged joints

Researchers have identified stem cells that can make new cartilage and repair damaged joints. The cells reside within the temporomandibular joint (TMJ), which articulates the jaw bone to the skull. When the stem cells were manipulated in animals with TMJ degeneration, the cells repaired cartilage in the joint.

A single cell transplanted in a mouse spontaneously generated cartilage and bone and even began to form a bone marrow niche. The study was published in Nature Communications.

Hearing Loss Caused By Alport Syndrome

Alport Syndrome is a genetic disease characterized by progressive hearing loss, as well as kidney disease and eye abnormalities. In Alport syndrome, a mutation in one of the genes that encode for the structural protein type 4 collagen causes problems in how the protein is made and functions.

Why is hearing affected by Alport syndrome?

Type 4 collagen is important in forming the organ of Corti (part of the cochlea), the portion of the inner ear that transforms sounds into electrical signals sent to the brain via auditory nerves. Structural abnormalities caused by the mutations lead to hearing loss, which can develop into profound deafness in some patients.