All news from Anaesthesiology

Menopausal Hormone Therapy: Primary Prevention of Chronic Conditions

To update the 2012 US Preventive Services Task Force (USPSTF) recommendation on the use of menopausal hormone therapy for the primary prevention of chronic conditions. It bases its recommendations on the evidence of both the benefits and harms of the service and an assessment of the balance. The USPSTF does not consider the costs of providing a service in this assessment. 

Ear Anatomy And Its Functions

According to this study, a widespread occurrence of middle-ear disease and the difficulty of accurately identifying the cause of conductive hearing loss, non-invasive, cost-effective diagnostic tools that reliably distinguish among middle-ear pathologies would be valuable. It supports in better selection of cases for surgery, surgical preparation, patient counselling, as well as help prevent unnecessary surgeries.

Stem cell approach sheds light on heart disease

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.

The team, led by Morgridge Institute Fellow Dave Vereide, describes in the issue of Stem Cell Research a new method of creating human arterial endothelial cells from cord blood and adult bone marrow sources. These cells, which have been notoriously difficult to grow in stable quantities, are essential to any future tissue engineering efforts to combat heart disease.

Malaria's 'Achilles heel': Structural clue to attack revealed

Researchers from The Scripps Research Institute (TSRI) and PATH's Malaria Vaccine Initiative (MVI) have shed light on how the human immune system recognizes the malaria parasite though investigation of antibodies generated from the RTS,S malaria vaccine — work that could boost the development of a more potent vaccine against the global killer.

Validation Of Immunoglobulin Gene Repertoire Method In Mice Tissue On ISS

In this research study, Spaceflight is known to affect immune cell populations. Splenic B cell numbers decrease during spaceflight and in ground-based physiological models. Although antibody isotype changes have been assessed during and after space flight, an extensive characterization of the impact of spaceflight on antibody composition has not been conducted in mice. Next Generation Sequencing and bioinformatic tools are now available to assess antibody repertoires.