All news from Anaesthesiology

Novel Tuberculosis Vaccine Offers Better Protection

A unique platform that resulted in a promising HIV vaccine has also led to a new, highly effective vaccine against tuberculosis that is moving toward testing in humans. The new vaccine completely protected 41% and reduced overall TB disease by 68% in vaccinated rhesus macaques, according to a study published as an Advanced Online Publication of Nature Medicine.

More Insights on Bladder Control

About 40% of older women and up to 35% of older men live with distressing urinary symptoms, including difficulty with bladder control and urinating (sometimes known as "voiding"), which often compromise the quality of life and overall health.

The lack of truly effective and safe therapies for these challenges stems from insufficient knowledge of the biological mechanisms for urinary control, the impact of aging and disease on urinary control, and the relationships of symptoms to urinary health and overall well-being. 

Brain MRI and AI could Help Children with Hearing Loss

A new study, published in the journal Proceedings of the National Academy of Sciences, described a machine learning algorithm that uses brain scans to predict language ability in deaf children after they receive a cochlear implant. This study's novel use of MRI and artificial intelligence to understand brain structure underlying language development has broad-reaching implications for children with developmental challenges.

Antipsychotics are Safer for Symptoms of Dementia

A new study has shown that primary care physicians (PCPs) continue to prescribe medications for behavioural and psychological symptoms of dementia (BPSD) because they view them as safer and more effective than controlled studies report. PCPs use drugs for symptoms with a direct threat of harm but also to meet patient-oriented goals, including easing patient suffering.

Cardiotoxicity testing using In Vitro and In Vivo models

Renal and hepatotoxicity of diglycolic acid (DGA) has been described with in vitro cellular models as well as in vivo animal and human systems. The possibility of diglycolic acid (DGA) being toxic to other organs, such as the heart, has not been well investigated. A human case report identified the heart as a potential target organ of DGA, but an in-house in vivo rat study neither found gross nor microscopic pathological changes following repeated oral DGA exposure.